Accuracy of digital angiography for quantitation of normal coronary luminal segments in excised, perfused hearts.
Accuracy of digital angiography for quantitation of normal coronary luminal segments in excised, perfused hearts.
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数字血管造影对切除、灌注心脏中正常冠状动脉腔段进行定量的准确性。
DOI：
10.1016/0002-9149(87)90901-5
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
Bashore,TM
中科院分区：
文献类型：
--
作者：
Skelton,TN;Kisslo,KB;Mikat,EM;Bashore,TM
通过对离体犬和人心脏的39个冠状动脉节段进行成像，并将这些节段与管腔直径为0.76至3.31 mm的病理切片进行比较，评估数字血管造影术测定冠状动脉直径的准确性。数字图像是死后获得的对比剂注射期间使用固定压力冠状动脉灌注系统和固定后，冠状动脉的大小是通过注射钡明胶铸造混合物保持。数字化数据用市售的自动边缘检测软件进行分析，使用冠状动脉导管作为校准标准，在造影剂注射过程中测量的冠状动脉直径与铸造和固定后测量的直径没有显著差异。两种方法的数字数据与病理切片的直径相关性良好（注射，r = 0.85;固定，r = 0.91）。将病理直径与对比剂注射方法进行比较的线性回归参数为斜率= 0.82，截距= 0.42 mm，估计标准误差= 0.27 mm。将病理直径与铸造冠状动脉数据进行比较的参数为斜率= 0.95，截距= 0.16 mm，估计值的标准误= 0.23 mm。观察者内和观察者间变异性分别为3%（0.05 mm）和4%（0.07 mm）。这些数据表明，当使用冠状动脉导管作为校准标准时，可以通过自动数字血管造影技术准确测量冠状动脉尺寸。
The accuracy of coronary artery diameter determination by digital angiography was assessed by imaging 39 coronary segments of excised dog and human hearts and comparing these segments with pathologic sections 0.76 to 3.31 mm in luminal diameter. Digital images were obtained postmortem both during contrast injection using a fixed-pressure coronary perfusion system and after fixation when the coronary size was maintained by injection of a barium-gelatin casting mixture. Digital data were analyzed with commercially available, automated edge-detection software using a coronary catheter as the calibration standard.Coronary diameter measured during contrast injection was not significantly different from that measured after casting and fixation. Digital data from both methods correlated well with diameters from pathologic sections (injected, r = 0.85; fixed, r = 0.91). Linear regression parameters comparing pathologic diameters with the contrast injection method were slope = 0.82, intercept = 0.42 mm, and standard error of the estimate = 0.27 mm. Parameters for the comparison of pathology with casted coronary data were slope = 0.95, intercept = 0.16 mm, and standard error of the estimate = 0.23 mm. Intra- and interobserver variability were 3% (0.05 mm) and 4% (0.07 mm), respectively. These data indicate that when a coronary catheter as a calibration standard is used, coronary artery dimensions can be accurately measured by automated digital angiography techniques.
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DOI：
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发表时间：
1983
期刊：
Springer: New York
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