Shigatoxigenic Escherichia coli (STEC) infections in Finland during 1998-2002:: a population-based surveillance study
Shigatoxigenic Escherichia coli (STEC) infections in Finland during 1998-2002:: a population-based surveillance study
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DOI：
10.1017/s0950268805004450
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发表时间：
2005-10-01
影响因子：
4.2
通讯作者：
Siitonen, A
中科院分区：
文献类型：
--
作者：
Eklund, M;Nuorti, JP;Siitonen, A
在1998-2002年期间，芬兰报告了124例经微生物学证实的由产志贺毒素大肠杆菌（STEC）引起的感染。其中25人（20%）与最近的国外旅行有关。进一步分析了O 157群（52例）和非O 157群（47例）引起的99例国内感染的时间、地理和型分布。患者的中位年龄为6岁。8年（范围0（.）2-73（.）1年）。在26个家庭中，71%的指示病例< 5岁。家庭相关感染占49%，散发感染占39%，3个聚集性感染占11%。只有携带eae和Stx（2）或其变异株的血清群0157菌株引起单独的聚类。1998年，STEC感染的发病率最高（0-64/100 000）。自1999年以来，这一数字大幅下降（0）。2002年为17/100 000）。STEC感染发生在14个医院区，大多数（28%）在赫尔辛基地区。然而，发病率最高（10（.）3)在芬兰西北部。
During 1998-2002, 124 microbiologically confirmed infections caused by shigatoxigenic Escherichia coli (STEC) were reported in Finland. Of these, 25 (20%) were associated with recent foreign travel. Temporal, geographical and type distribution of the domestically acquired infections (n = 99) caused by strains of serogroup O157 (n = 52) and non-O157 (n = 47) were analysed further. The median age of the patients was 6(.)8 years (range 0(.)2-73(.)1 years). Of the index cases within 26 families, 71% were < 5 years old. Family-related infections accounted for 49%, sporadic infections 39%, and 11% were associated with three clusters. Only strains of serogroup 0 157 carrying eae and Stx(2) or its variants caused separate clusters. The incidence of STEC infections was at its highest (0-64/100 000) in 1998. Since 1999 it has declined considerably (0(.)17/100 000 in 2002). STEC infections occurred in 14 hospital districts, mostly (28%) in the Helsinki region. However, the incidence was highest (10(.)3) in northwest Finland.