Self-assembled three-dimensional chiral colloidal architecture
Self-assembled three-dimensional chiral colloidal architecture
复制标题
DOI：
10.1126/science.aan5404
复制
发表时间：
2017-11-03
期刊：
影响因子：
56.9
通讯作者：
Chaikin, Paul M.
中科院分区：
文献类型：
--
作者：
Ben Zion, Matan Yah;He, Xiaojin;Chaikin, Paul M.
虽然立体化学自巴斯德以来一直是分子科学的中心焦点，但它的范围以前仅限于纳米尺度。我们已经编程的自组装的微米大小的胶体团簇的结构信息来自纳米排列。这是通过将DNA纳米技术与胶体科学相结合来完成的。利用DNA折纸的功能灵活性与胶体颗粒的结构刚性相结合，我们展示了三维微结构的平行自组装，表现出高度特定的几何形状，包括控制位置，二面角，和集群手性。
Although stereochemistry has been a central focus of the molecular sciences since Pasteur, its province has previously been restricted to the nanometric scale. We have programmed the self-assembly of micron-sized colloidal clusters with structural information stemming from a nanometric arrangement. This was done by combining DNA nanotechnology with colloidal science. Using the functional flexibility of DNA origami in conjunction with the structural rigidity of colloidal particles, we demonstrate the parallel self-assembly of three-dimensional microconstructs, evincing highly specific geometry that includes control over position, dihedral angles, and cluster chirality.