Hypomagnetic fields cause anxiety in adult male mice
Hypomagnetic fields cause anxiety in adult male mice
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低磁场导致成年雄性小鼠焦虑
DOI：
10.1002/bem.22155
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发表时间：
2019-01-01
影响因子：
1.9
通讯作者：
Hua, Qian
中科院分区：
文献类型：
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作者：
Ding, Hai-min;Wang, Xue;Hua, Qian
低磁场（HMF），即地磁场（GMF）的消除，是对外层空间宇航员健康的一个风险因素。已经确定，连续的HMF暴露影响细胞骨架组装、细胞增殖、胚胎发育，甚至学习和记忆。此外，尽管之前有一些研究关注长期HMF暴露的影响，但到目前为止，在动物中进行的短期HMF影响研究非常有限。在这项研究中，我们将成年雄性C57 BL/6小鼠暴露于3轴Helmholtz线圈HMF模拟系统72小时，发现短期HMF暴露诱导焦虑相关行为显著增加。研究结果为航天员的心理干预和健康护理提供了重要信息。生物电磁学40：27-32，2019.© 2018 Wiley Periodicals，Inc.
Hypomagnetic fields (HMF), that is, the elimination of the geomagnetic field (GMF), are a risk factor to the health of astronauts in outer space. It has been established that continuous HMF exposure affects cytoskeleton assembly, cell proliferation, embryonic development, and even learning and memory. In addition, although there were some previous studies that focused on the effects of long‐term HMF‐exposure, so far very limited investigations have been conducted to examine the short‐term HMF effect in animals. In this study, we exposed adult male C57BL/6 mice to a 3‐axis Helmholtz‐coil HMF‐simulation system for 72 h and found that short‐term HMF‐exposure induced a significant increase in anxiety‐related behaviors. And our findings provide important information for both psychological intervention and the health care of astronauts. Bioelectromagnetics. 40:27–32, 2019. © 2018 Wiley Periodicals, Inc.