The role of childhood abuse in Axis I and Axis II psychiatric disorders and medical disorders of unknown origin among irritable bowel syndrome patients.
The role of childhood abuse in Axis I and Axis II psychiatric disorders and medical disorders of unknown origin among irritable bowel syndrome patients.
复制标题
儿童期虐待在肠易激综合征患者中轴 I 和轴 II 精神疾病和不明原因的医学疾病中的作用。
DOI：
10.1016/s0022-3999(03)00627-5
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Sykes,MarkA
中科院分区：
文献类型：
--
作者：
Blanchard,EdwardB;Keefer,Laurie;Lackner,JeffreyM;Galovski,TaraE;Krasner,Susan;Sykes,MarkA
目的肠易激综合征(IBS)患者在寻求治疗的患者中，早期虐待和精神病理学的发生率很高。本研究的目的是进一步探讨IBS与早期滥用、Axis I和Axis II精神病理学以及其他医学上无法解释的障碍之间的关系。方法对196例寻求非药物治疗的IBS患者的胃肠道(GI)状态、精神状态(Axis I和Axis II)、早期滥用状态以及是否存在其他功能障碍进行了特征分析。结果和结论尽管IBS人群中存在较高水平的轴心II障碍或其他功能健康状况，但滥用组和非滥用组之间在轴II障碍的存在或其他功能健康状况方面没有显著差异。有滥用史的患者更有可能符合轴I障碍的标准，特别是物质滥用障碍、恶劣心境障碍和广泛性焦虑障碍。
OBJECTIVEHigh rates of early abuse and psychopathology are commonly reported among treatment-seeking patients with irritable bowel syndrome (IBS). The purpose of this study is to further explore the relations among IBS, early abuse, Axes I and II psychopathology, and other medically unexplained disorders.METHODSOne hundred and ninety-six IBS patients seeking nondrug treatment for their symptoms were characterized in terms of their gastrointestinal (GI) status, psychiatric status (Axis I and Axis II), early abuse status, and the presence of other functional disorders. Patients were divided into two groups based on early abuse status.RESULTS AND CONCLUSIONNo significant differences emerged between abused and nonabused groups on either the presence of Axis II disorders or other functional health conditions, although there were high levels of both in the IBS population. Patients with a history of abuse were significantly more likely to meet criteria for an Axis I disorder, especially substance abuse disorders, dysthymia, and generalized anxiety disorder.