Distribution of pore sizes in black lipid membranes treated with nystatin.

Distribution of pore sizes in black lipid membranes treated with nystatin.
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用制霉菌素处理的黑色脂质膜的孔径分布。

DOI:
10.1016/0005-2736(88)90321-5
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发表时间:
1988
期刊:
Biochimica et biophysica acta
影响因子:
--
通讯作者:
C. Gonzalez
C. Gonzalez
中科院分区:
--
文献类型:
--
作者:
M. Moreno;M. Bonilla;C. Gonzalez

文献摘要

被引文献

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用制霉菌素处理氧化胆固醇制成的人工膜,测量其阻力变化。实验数据被平滑,然后使用最大似然法对高斯函数的混合物进行拟合;最好的拟合是四个高斯函数的混合物,其中心大约为每孔4、6、9和12个分子,从而得出结论:这些是最可能的孔尺寸。
Resistance changes were measured on artificial membranes made of oxydized cholesterol and treated with nystatin. The experimental data were smoothed and then fitted to a mixture of Gaussian functions using the maximum likelihood method; the best fit was to a mixture of four gaussians centered approximately at 4, 6, 9 and 12 molecules per pore, leading to the conclusion that these are the most likely pore sizes.