The relationship of gender to pain, pain behavior, and disability in osteoarthritis patients: the role of catastrophizing
The relationship of gender to pain, pain behavior, and disability in osteoarthritis patients: the role of catastrophizing
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DOI：
10.1016/s0304-3959(00)00296-7
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发表时间：
2000-09-01
期刊：
影响因子：
7.4
通讯作者：
Caldwell, DS
中科院分区：
文献类型：
--
作者：
Keefe, FJ;Lefebvre, JC;Caldwell, DS
168例膝关节骨关节炎（OA）患者参加了本研究。参与者中，男性72人，女性96人。所有参与者完成关节炎影响测量量表（AIMS），进行10分钟的标准化观察，以评估他们的疼痛行为，并完成应对策略问卷（CSQ）中的灾难化量表和症状自评量表90修订版（SCL-90 R）中的抑郁量表。研究发现，患有OA的男性和女性在疼痛、疼痛行为和身体残疾方面存在显著差异。女性的疼痛和身体残疾程度明显高于男性，在观察期间表现出更多的疼痛行为。进一步的分析表明，灾难化介导的性别和疼痛相关的结果之间的关系。一旦灾难化被纳入分析，以前性别的显著影响就不再存在了。有趣的是，即使在控制了抑郁症之后，灾难化仍然介导了性别与疼痛的关系。这些发现强调了性别和灾难化在理解OA疼痛体验中的重要性，并可能对疼痛评估和治疗产生重要影响。(C)2000年国际疼痛研究协会。由Elsevier Science B. V.出版，版权所有。
One hundred and sixty-eight patients with osteoarthritis (OA) of the knees participated in this study. Of the participants, 72 were men and 96 wen women. All participants completed the Arthritis Impact Measurement Scales (AIMS), underwent a 10 min standardized observation session to assess their pain behavior, and completed the Catastrophizing Scale of the Coping Strategies Questionnaire (CSQ) and the Depression Scale of the Symptom Checklist 90 Revised (SCL-90R). The study found that there were significant differences in pain, pain behavior, and physical disability in men and women having OA. Women had significantly higher levels of pain and physical disability, and exhibited more pain behavior during an observation session than men. Further analyses revealed that catastrophizing mediated the relationship between gender and pain-related outcomes. Once catastrophizing was entered into the analyses, the previously significant effects of gender were no longer found. Interestingly, catastrophizing still mediated the gender-pain relationship even after controlling for depression. These findings underscore the importance of both gender and catastrophizing in understanding the OA pain experience and may have important implications for pain assessment and treatment. (C) 2000 International Association for the Study of Pain. Published by Elsevier Science B.V. All rights reserved.