ELECTRONIC-STRUCTURE CONTRIBUTIONS TO FUNCTION IN BIOINORGANIC CHEMISTRY
ELECTRONIC-STRUCTURE CONTRIBUTIONS TO FUNCTION IN BIOINORGANIC CHEMISTRY
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DOI：
10.1126/science.8384374
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发表时间：
1993-03-12
期刊：
影响因子：
56.9
通讯作者：
LOWERY, MD
中科院分区：
文献类型：
--
作者：
SOLOMON, EI;LOWERY, MD
许多金属酶表现出独特的光谱特征，这些特征现在已经得到了很好的理解。这些反映了对催化有重要贡献的活性位点电子结构。铜蛋白提供了表征良好的例子，其中其活性位点的不寻常电子结构有助于快速，远程电子转移反应活性，氧结合和活化，以及双氧多电子还原为水。
Many metalloenzymes exhibit distinctive spectral features that are now becoming well understood. These reflect active site electronic structures that can make significant contributions to catalysis. Copper proteins provide well-characterized examples in which the unusual electronic structures of their active sites contribute to rapid, long-range electron transfer reactivity, oxygen binding and activation, and the multielectron reduction of dioxygen to water.