CAUSE-SPECIFIC MORTALITY IN A POPULATION-BASED STUDY OF DIABETES
CAUSE-SPECIFIC MORTALITY IN A POPULATION-BASED STUDY OF DIABETES
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DOI：
10.2105/ajph.81.9.1158
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发表时间：
1991-09-01
影响因子：
12.7
通讯作者：
KLEIN, BEK
中科院分区：
文献类型：
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作者：
MOSS, SE;KLEIN, R;KLEIN, BEK
背景据报道，糖尿病患者的血管疾病死亡率很高。为了评估这些和其他特定原因的死亡率，我们在地理上定义的年轻发病（30岁之前诊断并服用胰岛素，n = 1200）和老年发病（30岁之后诊断，n = 1772）糖尿病患者中检查了病因特异性年龄性别标准化死亡率，随访时间为8.5年。根据死亡证明确定死亡原因。在发病年龄较轻的人群中，年龄-性别标准化死亡率在所有死因（7.5）、糖尿病（191）、所有心脏病（9.1）、缺血性心脏病（10.1）、其他心脏病（6.3）、肾炎和肾病（41.2）、事故（2.9）和所有其他原因（3.2）方面均显著较高（P <0.05）。在老年发病人群中，年龄-性别标准化死亡率在所有死因（2.0）、糖尿病（16.8）、所有心脏病（2.3）、缺血性心脏病（2.3）、其他心脏病（2.1）、中风（2.0）、肺炎和流感（1.7）中均显著较高。与一般人群相比，糖尿病患者的死亡率非常高，尤其是血管疾病。
Background. Mortality from vascular diseases has been reported to be high in diabetic persons.Methods. To evaluate mortality from these and other specific causes, we examined cause-specific age-sex standardized mortality ratios in a geographically defined population of younger onset (diagnosed before age 30 and taking insulin, n = 1200) and older onset (diagnosed after age 30, n = 1772) diabetic persons followed for 8.5 years. Cause of death was determined from death certificates.Results. In younger onset persons, age-sex standardized mortality ratios were significantly high (P < .05) for all causes of death (7.5) as well as for diabetes (191), all heart disease (9.1), ischemic heart disease (10.1), other heart disease (6.3), nephritis and nephrosis (41.2), accidents (2.9), and all other causes (3.2). In older onset persons, age-sex standardized mortality ratios were significantly high for all causes of death (2.0) as well as for diabetes (16.8), all heart disease (2.3), ischemic heart disease (2.3), other heart disease (2.1), stroke (2.0), and pneumonia and influenza (1.7).Conclusions. Diabetic persons experience very high mortality, especially from vascular disease, compared to the general population.