Stranger in a strange land: roles of glycogen turnover in adipose tissue metabolism.
Stranger in a strange land: roles of glycogen turnover in adipose tissue metabolism.
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DOI：
10.1016/j.mce.2009.08.013
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发表时间：
2010-04-29
影响因子：
4.1
通讯作者：
Brady, Matthew J.
中科院分区：
文献类型：
--
作者：
Markan, Kathleen R.;Jurczak, Michael J.;Brady, Matthew J.
Triglyceride storage in adipose tissue comprises the principal energy reserve in mammals. Additionally glucose can be stored as glycogen in the fed state, primarily in liver and skeletal muscle, for mobilization during times of energy deficit. Adipose tissue also contains glycogen stores albeit at very low levels. The physiological role of glycogen metabolism in adipocytes remains unclear. However, both classical literature and more recent work demonstrate that the dynamic regulation of adipose glycogen may serve as an energy sensing modality in the coordination of glucose and lipid metabolism in adipose tissue, especially during the fasted to fed transition.
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