Transperitoneal vs. extraperitoneal radical cystectomy for bladder cancer: A retrospective study

Transperitoneal vs. extraperitoneal radical cystectomy for bladder cancer: A retrospective study
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DOI:
10.1590/s1677-5538.ibju.2017.0441
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发表时间:
2018-04-01
影响因子:
3.7
通讯作者:
Agarwal, Himanshu
Agarwal, Himanshu
中科院分区:
医学4区
文献类型:
--
作者:
Kulkarni, Jagdeesh N.;Agarwal, Himanshu

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目的:传统经腹膜根治性膀胱切除术(TPRC)是治疗肌层浸润性膀胱癌的标准方法。但是,该手术与尿漏、肠梗阻和感染等严重并发症有关。为了减少这些发病率,我们于 1999 年描述了腹膜外根治性膀胱切除术 (EPRC) 技术。我们比较了这两种方法,积累的数据构成了本报告的基础。材料和方法:作者 (JNK) 纳入了所有因膀胱癌接受根治性膀胱切除术并随访至少 5 年的患者。共纳入338例患者,其中EPRC组180例,TPRC组158例。结果:TPRC组30天内死亡3例,EPRC组1例。 EPRC组和TPRC组的早期并发症发生率分别为52%和58%。 31 名患者 (9.2%) 发生尿漏(EPRC 13 名,TPRC 18 名,p=0.19)。 EPRC 组有 9 例(5%)患者出现肠梗阻等胃肠道并发症,TPRC 组有 25 例(15.8%)患者出现肠梗阻等胃肠道并发症(p
Purpose: Conventional transperitoneal radical cystectomy (TPRC) is the standard approach for muscle invasive bladder cancer. But, the procedure is associated with significant morbidities like urinary leak, ileus, and infection. To reduce these morbidities, the technique of extraperitoneal radical cystectomy (EPRC) was described by us in 1999. We compared these two approaches and the data accrued forms the basis of this report.Materials and Methods: All patients who underwent radical cystectomy for bladder cancer by the author (JNK) with follow-up for at least 5 years were included. A total of 338 patients were studied, with 180 patients in EPRC group and 158 in TPRC group.Results: There were 3 mortalities within 30 days in TPRC group and one in EPRC group. Early complication rate was 52% and 58% in EPRC and TPRC groups. Urinary leak occurred in 31 (9.2%) patients (13 in EPRC, 18 in TPRC, p=0.19). Gastrointestinal complications like ileus occurred in 9 (5%) patients in EPRC group and in 25 (15.8%) patients in TPRC group, (p