A combined strategy to improve the control of Schistosoma mansoni in areas of low prevalence in Brazil
A combined strategy to improve the control of Schistosoma mansoni in areas of low prevalence in Brazil
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DOI：
10.4269/ajtmh.2008.78.140
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发表时间：
2008-01-01
影响因子：
3.3
通讯作者：
Schall, Virginia Torres
中科院分区：
文献类型：
--
作者：
Enk, Martin Johannes;Lustosa Lima, Anna Carolina;Schall, Virginia Torres
生活在巴西米纳斯吉拉斯州的一个村庄的学龄儿童中曼氏血吸虫感染的粪便检查结果被用作在整个人群中识别曼氏血吸虫阳性个体的指标。这一新方法的基础是将社区划分为学龄儿童、有残疾和无残疾学龄儿童的家庭成员以及没有学龄儿童的家庭成员。对每个亚组进行评估，将不同的采样努力与预定的“金标准”进行比较，以找到检出率和采样努力之间的最佳关系。因此，这些结果被合并，并制定了一项适用于整个社区的新战略提案。在筛查过程中的这种替代方法允许处理与用3份粪便样本的6个Kato-Katz载玻片检测到的阳性比例相似的阳性，采样减少了3倍，努力提高了低流行地区血吸虫病控制计划的效率。
Results of stool examinations for infections with Schistosoma mansoni among schoolchildren, living in a villa-Re of Minas Gerais State, Brazil, were used as an indicator to identify schistosomiasis-positive individuals within the entire population. This new approach is based on dividing the community into schoolchildren, members of households of schistosomiasis-positive and -negative schoolchildren, and members of households without schoolchildren. Each subgroup was evaluated comparing different sampling efforts with the predetermined "gold standard" to find the best relationship between detection rate and sampling effort. Consequently these results were combined, and a proposal for a new strategy, valid for an entire community, was elaborated. This alternative approach during the screening process permits to treat a similar proportion of positives as detected with 6 Kato-Katz slides of 3 stool samples, with 3-fold reduced sampling, effort, enhancing the efficiency of schistosomiasis control programs in low-endemic areas.