Electrocardiographic variables associated with underlying Brugada syndrome or drug-induced Type 1 Brugada pattern in patients with slow/fast atrioventricular nodal reentrant tachycardia.
Electrocardiographic variables associated with underlying Brugada syndrome or drug-induced Type 1 Brugada pattern in patients with slow/fast atrioventricular nodal reentrant tachycardia.
复制标题
DOI：
10.1002/joa3.12729
复制
发表时间：
2022-08
影响因子：
2
通讯作者：
Antzelevitch, Charles
中科院分区：
文献类型：
--
作者：
Hasdemir, Can;Sahin, Hatice;Duran, Gulten;Orman, Mehmet N.;Kocabas, Umut;Payzin, Serdar;Aydin, Mehmet;Antzelevitch, Charles
关键词：
临床房室结折返性心动过速（AVNRT）和药物诱导的1型Brugada模式（DI - 1型BrP）共存已有报道。本研究旨在确定基线和AVNRT期间的12导联心电图特征，并确定慢/快AVNRT患者中与潜在Brugada综合征(BrS)/DI - 1型BrP相关的12导联心电图变量的一个亚组。共分析了40项（11项数值/29项分类）12导联心电图参数，并在年龄、女性性别、体重指数、左室射血分数和合并症相匹配的BrS/DI‐type - 1‐BrP患者（n = 69）和非BrP患者（n = 104）之间进行了比较。AVNRT期间V1-V2导联的心电图类型分为A/B/C/D/E五种。总共确定了9个心电图变量，4个在基线时，5个在AVNRT期间。在基线时，与没有BrS/DI‐1型BrP的患者相比，BrS/DI‐1型BrP患者的房间传导阻滞、额平面QRS轴向左移位、V1-V2无正常QRS模式（存在rSr '模式或2/3型Brugada模式）和下导联QRS碎裂的发生率更高。在AVNRT期间，与没有BrS/DI - 1型BrP的患者相比，BrS/DI - 1型BrP患者在V1 - V2中具有更高的A型ECG模式（“覆盖型”ST段抬高）、C型ECG模式（V1伪r ‘偏转和V2“RBBB样”模式）、V1伪r ’偏转、下导联QRS碎片化和aVL“孤立性”QRS碎片化/缺口/模糊。我们确定了几个心电图变量，这些变量指向慢/快AVNRT患者潜在的1型BrP。在临床自发性房室结折返性心动过速（AVNRT）患者中，共有9个心电图变量可预测潜在的1型Brugada模式（BrP）。总结了1型BrP和AVNRT共存的意义。
The coexistence of clinical atrioventricular nodal reentrant tachycardia (AVNRT) and drug‐induced type 1 Brugada pattern (DI‐Type 1 BrP) has been previously reported. The present study was designed to determine the 12‐lead ECG characteristics at baseline and during AVNRT and to identify a subset of 12‐lead ECG variables of benefit associated with underlying Brugada syndrome (BrS)/DI‐Type 1 BrP among patients with slow/fast AVNRT. A total of 40 (11 numerical/29 categorical) 12‐lead ECG parameters were analyzed and compared between patients with (n = 69) and without (n = 104) BrS/DI‐Type1‐BrP matched for age, female gender, body mass index, left ventricular ejection fraction and comorbid conditions. Five distinct types of ECG pattern (Type A/B/C/D/E) in V1–V2 leads during AVNRT were defined. A total of nine electrocardiographic variables, four at baseline, and five during AVNRT were identified. At baseline, patients with BrS/DI‐Type 1 BrP had higher prevalence of interatrial block, leftward shift of frontal plane QRS axis, the absence of normal QRS pattern (the presence of rSr’ pattern or type 2/3 Brugada pattern) in V1–V2 and QRS fragmentation in inferior leads compared to patients without BrS/DI‐Type 1 BrP. During AVNRT, patients with BrS/DI‐Type 1 BrP had higher prevalence of Type A ECG pattern (“coved‐type” ST‐segment elevation) in V1–V2, Type C ECG pattern (pseudo‐r’ deflection in V1 and “RBBB‐like” pattern in V2), pseudo‐r’ deflection in V1, QRS fragmentation in inferior leads and “isolated” QRS fragmentation/notching/slurring in aVL compared to patients without BrS/DI‐Type 1 BrP. We identify several electrocardiographic variables that point to an underlying type 1 BrP among patients with slow/fast AVNRT. A total of 9 electrocardiographic variables predicting underlying type 1 Brugada Pattern (BrP) among patients with clinical, spontaneous atrioventricular nodal reentrant tachycardia (AVNRT) were identified. Implications of co‐existence of type 1 BrP and AVNRT were summarized.
登录
查看更多内容
影响因子：
5.5
作者：
Bigi, Mohamad Ali Babai;Aslani, Amir;Shahrzad, Shahab
通讯作者：
Shahrzad, Shahab
DOI：
10.1111/pace.13414
发表时间：
2018-09
期刊：
Pacing and clinical electrophysiology : PACE
影响因子：
--
作者：
Hasdemir C;Juang JJ;Kose S;Kocabas U;Orman MN;Payzin S;Sahin H;Celen C;Ozcan EE;Chen CJ;Gunduz R;Turan OE;Senol O;Burashnikov E;Antzelevitch C
通讯作者：
Antzelevitch C
影响因子：
7
作者：
Russo, Vincenzo;Pafundi, Pia Clara;Nesti, Martina
通讯作者：
Nesti, Martina
影响因子：
5.6
作者：
van der Ree MH;Vendrik J;Kors JA;Amin AS;Wilde AAM;Tan HL;Postema PG
通讯作者：
Postema PG
影响因子：
39.3
作者：
Bussink, Barbara E.;Holst, Anders G.;Prescott, Eva
通讯作者：
Prescott, Eva