Circadian Sleep Patterns in Toddlers Born Preterm: Longitudinal Associations with Developmental and Health Concerns.
Circadian Sleep Patterns in Toddlers Born Preterm: Longitudinal Associations with Developmental and Health Concerns.
复制标题
早产儿的昼夜节律睡眠模式：与发育和健康问题的纵向关联。
DOI：
10.1097/dbp.0000000000000287
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
Poehlmann-Tynan,JulieA
中科院分区：
文献类型：
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作者：
Schwichtenberg,AmyJ;Christ,Sharon;Abel,Emily;Poehlmann-Tynan,JulieA
目的：早产儿童在几种发育和健康问题上的风险较高。早睡模式可能与这些担忧有关。目前的研究评估了这一高危人群中幼儿昼夜睡眠/活动模式与后期发育、行为、注意力和健康问题之间的关系。方法：我们检查了99名早产儿童2岁时的昼夜睡眠/活动模式。在儿童3岁时测试认知技能，在3岁和6岁时报告行为、注意力和健康问题。首先，通过活动记录仪收集的睡眠/活动数据使用时间序列分析（TSA）进行评估。为此，我们将每个孩子的睡眠/活动模式与指定的24小时昼夜节律周期（SCC）进行了比较，并对白天午睡进行了调整。其次，在一系列回归模型中，以儿童性别、早产和家庭社会人口资产为协变量评估TSA中的儿童睡眠/活动参数。结果：具有与SCC密切相关模式的幼儿在3岁时具有较高的缩略智商得分。此外，在6岁时，这些儿童因疾病就诊的风险较低。较高的幼儿平均活动水平与较少的教师报告的注意力缺陷多动障碍症状和较低的疾病相关医疗就诊风险相关。结论：本研究中用于索引儿童昼夜节律模式的新方法提供了基于模式的睡眠/活动分析，这可能被证明是发展的结果。通过重复研究，这些发现可能有助于从业者通过支持早产儿的昼夜节律睡眠来促进最佳的认知和健康发展。
Objective:Children born preterm are at elevated risk for several developmental and health concerns. Early sleep patterns may be associated with these concerns. The current study assesses the associations between toddler circadian sleep/activity patterns and later developmental, behavioral, attentional, and health concerns in this at-risk population.Method:We examined circadian sleep/activity patterns at 2 years of age in 99 children born preterm. Child cognitive skills were tested at 3 years of age, and behavior, attention, and health concerns were reported at 3 and 6 years of age. First, sleep/activity data collected via actigraphy were assessed using time series analysis (TSA). For this, we assessed how each child's sleep/activity pattern compared to a specified 24-hour circadian cycle (SCC) with an adjustment for daytime napping. Second, in a series of regression models child sleep/activity parameters from the TSA were assessed with child gender, prematurity, and family sociodemographic assets as covariates.Results:Toddlers with patterns that closely aligned with the SCC had higher abbreviated intelligence quotient scores at 3 years of age. Additionally, at 6 years these children had a lower risk for illness-related medical visits. Higher toddler average activity level was associated with fewer teacher-reported attention-deficit hyperactivity disorder symptoms and a lower risk for illness-related medical visits.Conclusion:The novel approach used in this study to index child circadian patterns provides a pattern-based analysis of sleep/activity, which may prove to be developmentally consequential. With replication, these findings may help practitioners promote optimal cognitive and health development via circadian sleep supports in infants born preterm.