Fate of Host-Stabilized Charge Transfer Complexation Based on Cucurbit[8]uril: Inducing Cyclization of PNIPAM and Dissociation in Self-Assembly of the Cyclic Polymer
Fate of Host-Stabilized Charge Transfer Complexation Based on Cucurbit[8]uril: Inducing Cyclization of PNIPAM and Dissociation in Self-Assembly of the Cyclic Polymer
复制标题
基于葫芦[8]脲的主体稳定电荷转移络合的命运：诱导PNIPAM环化和环状聚合物自组装解离
DOI：
10.1021/acsmacrolett.6b00220
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发表时间：
2016
影响因子：
5.8
通讯作者：
Jiang Ming
中科院分区：
文献类型：
--
作者：
Ji Zhongwei;Li Junfang;Chen Guosong;Jiang Ming
基于葫芦[8]脲的主体稳定的电荷转移（HSCT）配合物已被广泛应用于构建新型超分子结构，并可进一步自组装成纳米物体。在组装过程中，HSCT相互作用的高稳定性总是被假定或默认的。然而，在自组装过程中的稳定性从来没有在以前的研究中得到很好的表征。在本工作中，我们首先通过CB[8]基HSCT相互作用实现了线性PNIPAM的环化。然后我们意外地发现，在热诱导的环状PNIPAM的自组装过程中，HSCT相互作用发生了解离。在这个过程中，带电荷的CB[8]络合物从环状聚合物的聚集体释放到溶液中，并且它可以被新加入的客体分子重新捕获。该HSCT解离由PNIPAM聚集体的疏水性和HSCT复合物的阳离子性质的不相容性驱动。据我们所知，这种组装诱导解离现象尚未在文献中报道。
Host-stabilized charge transfer (HSCT) complex based on cucurbit[8]uril has been widely used in building novel supramolecular structures, which could further self-assemble into nano-objects. High stability of the HSCT interaction during the assembly process is always assumed or defaulted. However, the stability during self-assembly has never been well characterized in previous studies. In this work, we realized cyclization of linear PNIPAM by CB[8]-based HSCT interaction first. And then we found unexpectedly that during the heating-induced self-assembly of the cyclic PNIPAM, dissociation of the HSCT interaction took place. In this process, charged CB[8] complex was released from the aggregates of the cyclic polymer to solution, and it could be recaptured by newly added guest molecules. This HSCT dissociation was driven by the incompatibility of the hydrophobicity of the PNIPAM aggregates and the cationic nature of the HSCT complex. To the best of our knowledge, this assembly induced dissociation phenomenon has not been reported in literature.