Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease.

Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease.
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DOI:
10.1111/j.1749-6632.2010.05848.x
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发表时间:
2011-01
影响因子:
5.2
通讯作者:
Csiszar A
Csiszar A
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Csiszar A

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心血管疾病是西方世界老年人最常见的死亡原因。白藜芦醇(3,5,4 ′-三羟基二苯乙烯)是一种植物来源的多酚,具有多种抗衰老活性,模拟热量限制的一些分子和功能效应。本文综述了白藜芦醇在血管系统中激活的分子和细胞机制,并探讨了其抗氧化和抗炎作用之间的联系,可用于预防或改善老年人血管老化。
Cardiovascular diseases are the most common cause of death among the elderly in the Western world. Resveratrol (3,5,4´-trihydroxystilbene) is a plant-derived polyphenol that was shown to exert diverse anti-aging activity mimicking some of the molecular and functional effects of caloric restriction. This mini-review focuses on the molecular and cellular mechanisms activated by resveratrol in the vascular system, and explores the links between its anti-oxidative and anti-inflammatory effects, which could be exploited for the prevention or amelioration of vascular aging in the elderly.
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