Immunostimulant and Antidepressant Effect of Natural Compounds in the Management of Covid-19 Symptoms
Immunostimulant and Antidepressant Effect of Natural Compounds in the Management of Covid-19 Symptoms
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DOI：
10.1080/07315724.2021.1965503
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发表时间：
2021-08-09
期刊：
影响因子：
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通讯作者：
Cicero, Nicola
中科院分区：
文献类型：
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作者：
Alesci, Alessio;Fumia, Angelo;Cicero, Nicola
近年来，使用天然化合物作为辅助治疗和传统药物治疗的替代品越来越受欢迎。这些化合物具有广泛的生物学作用，如：抗氧化、抗衰老、降胆固醇、降血糖、抗肿瘤、抗抑郁、抗焦虑等活性。几乎所有这些化合物都很容易获得，并包含在不同的食品中。2019年底，冠状病毒SARS-CoV-2在中国出现，并迅速蔓延到世界各地，造成大流行。这种感染最常见的症状是干咳、发热、呼吸困难，严重时会出现双侧间质性肺炎，其后果可导致死亡。这些国家为了防止感染蔓延，对本国公民实施了社交距离和封锁措施。这产生了强烈的心理社会影响，导致恐惧、焦虑和抑郁状态。药物治疗可以伴随着几种天然化合物的治疗，如维生素，黄芩素，锌和精油。这些化合物具有显著的免疫刺激活性，增强免疫应答并减轻病毒与宿主细胞之间的相互作用。它们还具有抗抑郁作用，作用于某些神经递质。[图形]。
In recent years, the use of natural compounds as adjuvant treatments and alternatives to traditional pharmacological therapies has become increasingly popular. These compounds have a wide range of biological effects, such as: antioxidant, anti-aging, hypocholesterolizing, hypoglycemic, antitumoral, antidepressant, anxiolytic activity, etc. Almost all of these compounds are easily available and are contained in different foods. At the end of 2019 the Coronavirus SARS-CoV-2 appeared in China and quickly spread throughout the world, causing a pandemic. The most common symptoms of this infection are dry cough, fever, dyspnea, and in severe cases bilateral interstitial pneumonia, with consequences that can lead to death. The nations, in trying to prevent the spread of infection, have imposed social distancing and lockdown measures on their citizens. This had a strong psychological-social impact, leading to phobic, anxious and depressive states. Pharmacological therapy could be accompanied by treatment with several natural compounds, such as vitamins, baicalein, zinc and essential oils. These compounds possess marked immunostimulant activity, strengthening the immune response and mitigating interactions between the virus and the host cell. They also have an antidepressant effect, acting on certain neurotransmitters.[GRAPHICS].