Detection of longitudinal change in periodontitis.
Detection of longitudinal change in periodontitis.
复制标题
检测牙周炎的纵向变化。
DOI：
10.1111/j.1600-0765.1989.tb00878.x
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发表时间：
1989
影响因子：
3.5
通讯作者：
Pihlstrom,BL
中科院分区：
文献类型：
--
作者：
Aeppli,DM;Pihlstrom,BL
在牙周炎的任何纵向研究中，重要的是尽快确定探测深度或临床附着水平何时发生变化。在本研究中，模拟用于比较三种统计方法，用于在各种条件下检测线性牙周测量的变化，包括变化类型、随访次数、线性测量的幅度和检查者方差。统计方法包括：1）测试回归线的斜率，2）运行中位数的比较和3）累积和（cusum）方法。对基线线性测量施加三种类型的变化和随机检查者误差。变化的类型包括逐渐变化、突发变化和快速损失然后再生。结果表明，当变化是渐进的时，所有三种方法都产生相似的结果。然而，与其他方法相比，回归线对突发变化的敏感度较低。高估运行中位数和累积方法的检查者误差会增加特异性并降低敏感性。低估检查者方差降低了累积和运行中位数方法的特异性并增加了敏感性，而回归不受检查者方差估计的影响。如果不需要立即采取预防或治疗措施，则运行中位数或累积值都是检测变化的不错选择。如果需要立即干预，cusum 似乎是纵向牙周研究中检测特定部位变化的首选方法。
In any longitudinal study of periodontitis, it is important to determine when change in probing depth or clinical attachment level occurs as soon as possible. In this study, simulation was used to compare three statistical methods for detecting change in linear periodontal measurement under a variety of conditions including type of change, number of follow‐up visits, magnitude of linear measurement and examiner variance. The statistical methods included: 1) testing the slope of a regression line, 2) a comparison of running medians and 3) the cumulative sum (cusum) method. Three types of change and random examiner error were imposed on baseline linear measurements. The types of change included a gradual change, a burst, and rapid loss followed by regeneration. The results indicated that all three methods yielded similar results when the change was gradual. However, the regression line was less sensitive to bursts of change than the other methods. Overestimation of examiner error for the running median and cusum methods increased specificity and decreased sensitivity. Underestimation of examiner variance decreased specificity and increased sensitivity of the cusum and running median methods, while the regression was unaffected by estimates of examiner variance. If preventive or therapeutic action does not need to be taken immediately, either the running median or the cusum would be a good choice for detecting change. If immediate intervention is needed, the cusum appears to be the method of choice for detecting change at specific sites in longitudinal periodontal studies.
影响因子：
6.7
作者：
BADERSTEN, A;NILVEUS, R;EGELBERG, J
通讯作者：
EGELBERG, J
影响因子：
6.7
作者：
GOODSON, JM;TANNER, ACR;SOCRANSKY, SS
通讯作者：
SOCRANSKY, SS