Effects of Alcohol Cue Exposure on Response Inhibition in Detoxified Alcohol-Dependent Patients
Effects of Alcohol Cue Exposure on Response Inhibition in Detoxified Alcohol-Dependent Patients
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DOI：
10.1111/j.1530-0277.2010.01243.x
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发表时间：
2010-09-01
影响因子：
3.2
通讯作者：
Staedtgen, Mario
中科院分区：
文献类型：
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作者：
Gauggel, Siegfried;Heusinger, Anne;Staedtgen, Mario
背景：有证据表明，在饮酒过程中进行自我控制会降低在随后需要自我控制的任务中的表现。基于资源耗竭模型(Muraven和Baumeister，2000)，我们考察了酒精线索暴露对脱毒酒依赖患者持续反应抑制能力的影响。方法：20名酒依赖患者被随机分配到酒精线索暴露和对照线索暴露两种条件下，然后被要求执行一项抑制任务(即停止信号任务)。结果：在执行抑制任务之前，嗅酒者报告了比吸水对照组更强烈的饮酒冲动。吸入酒精的受试者在停止信号任务中的抑制性表现也受到了损害，但他们的非抑制性表现并未受到影响。结论：饮酒的冲动可能降低了受试者的自控力，这干扰了他们抑制反应的能力。
Background:There is evidence that exerting self-control during alcohol craving can diminish performance on subsequent tasks that require self-control. Based on the resource depletion model (Muraven and Baumeister, 2000), we examined the influence of alcohol cue exposure on detoxified alcohol-dependent patients' ability to inhibit ongoing responses.Methods:Twenty alcohol-dependent patients were randomly assigned to an alcohol-cue exposure and a control-cue exposure condition and thereafter had to perform an inhibition task (i.e., stop-signal task).Results:Participants who sniffed alcohol before performing the inhibition task reported a stronger urge to drink alcohol than the control group that sniffed water. Participants who sniffed alcohol were also impaired in their inhibitory performance but not in their noninhibitory performance on the stop-signal task.Conclusions:The urge to drink presumably reduced participants' self-control, and this interfered with their ability to inhibit responding.