Reproducibility of repeated human regional splenic blood flow measurements using [15O] water and positron emission tomography
Reproducibility of repeated human regional splenic blood flow measurements using [15O] water and positron emission tomography
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DOI：
10.1097/00006231-200107000-00005
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发表时间：
2001-07-01
影响因子：
1.5
通讯作者：
Yamagishi, H
中科院分区：
文献类型：
--
作者：
Taniguchi, H;Kunishima, S;Yamagishi, H
评价了[O-15]水动态正电子发射断层扫描（PET）测量局部脾血流量的再现性。在19例患者中，第一次和第二次连续动态测量之间的相关性是显著的(P = 1.78 × 10(-6)；R = 0.858)。回归方程为y = 1.06x，曲线斜率的95%置信区间为0.09。两次测量之间的明显误差为0.129（95%置信区间为0.059）。结果表明，用PET和[O-15]水测量局部脾血流量具有足够好的重复性，建议使用该方法进行旨在检测变化的系列测量，包括药物效应。(C) 2001 Lippincott Williams & Wilkins)。
The reproducibility of measurement of regional splenic blood flow by dynamic positron emission tomography (PET) using [O-15]water was evaluated. In 19 patients, the correlation between the first and second of two serial dynamic measurements was significant (P = 1.78 x 10(-6); r = 0.858). The regression equation was y = 1.06x, and the slope of the line described had a 95% confidence interval of 0.09. The error apparent between the two measurements was 0.129 (95% confidence interval 0.059). The results demonstrated sufficiently good reproducibility for measurements of regional splenic blood flow with PET and [O-15]water to suggest use of this method for serial measurements intended to detect change, including drug effects. ((C) 2001 Lippincott Williams & Wilkins).