Association of physical and/or cognitive activity with cognitive impairment in older adults
Association of physical and/or cognitive activity with cognitive impairment in older adults
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DOI：
10.1111/ggi.13814
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发表时间：
2020-01-01
影响因子：
3.3
通讯作者：
Shimada, Hiroyuki
中科院分区：
文献类型：
--
作者：
Kurita, Satoshi;Tsutsumimoto, Kota;Shimada, Hiroyuki
目的研究日本名古屋社区老年人的体力活动(PA)和/或认知活动(CA)与认知功能障碍之间的关系。方法2726名受试者(平均年龄75.5±-3.9岁，51.8%为女性)符合研究标准。使用加速度计测量中度到重度PA的时间。通过参与六项活动(阅读、写作、填字游戏、玩棋盘游戏/纸牌、参加有组织的小组讨论和演奏乐器)的频率对CA进行主观评估。受试者根据高或低PA合并高或低CA分为四组。认知障碍的定义是至少四项神经心理测试中的一项，结果至少比参考阈值低1.5个标准差。结果低PA低CA组认知功能障碍发生率为29.5%，高PA高CA组为14.8%，差异有统计学意义(P<；0.001)。与低PA低CA组相比，低PA高CA组认知功能损害的OR值(OR：0.54，95%CI为0.37~0.79；高PA低CA组OR为0.64，95%CI为0.45~0.92；高PA高CA组OR为0.42，95%CI为0.30~0.58)。结论PA和CA对认知功能损害均有保护作用，即使其中一方参与程度较低。因此，老年人难以进行足够的PA可能受益于CA，以防止认知损害。Geriatr Gerontol Int 2020；20：31-35。
Aim We aimed to examine the association between physical activity (PA) and/or cognitive activity (CA) and cognitive impairment in a sample of older adults from a community-based cohort in Nagoya, Japan. Methods A total of 2726 participants (mean age 75.5 +/- 3.9 years; 51.8% women) met the study criteria. The time of moderate-to-vigorous intensity PA was measured using an accelerometer. CA was subjectively assessed by the frequency of engagement in six activities (reading, writing for pleasure, doing crossword puzzles, playing board games/cards, participating in organized group discussions and playing musical instruments). Participants were categorized into four groups by high or low PA combined with high or low CA. Cognitive impairment was defined by at least one of four neuropsychological tests with a result of at least 1.5 standard deviations below the reference threshold. Results The prevalence of cognitive impairments differed significantly between the groups (P < 0.001), with 29.5% in the low PA and low CA group, to 14.8% in the high PA and high CA group. Compared with the low PA and low CA group, other groups had significantly lower odds ratio (OR) of cognitive impairment (low PA and high CA: OR 0.54, 95% CI 0.37-0.79; high PA and low CA: OR 0.64, 95% CI 0.45-0.92; high PA and high CA: OR 0.42, 95% CI 0.30-0.58). Conclusions Both PA and CA showed a protective association with cognitive impairment, even when one or the other is lowly engaged. Therefore, older adults with difficulty engaging in sufficient PA might benefit from CA to prevent cognitive impairment. Geriatr Gerontol Int 2020; 20: 31-35.