The operator-binding domain of λ repressor: structure and DNA recognition
The operator-binding domain of λ repressor: structure and DNA recognition
复制标题
λ 阻遏物的操纵子结合域：结构和 DNA 识别
作者：
C. Pabo;M. Lewis
λ 阻遏物的操纵子结合域的结构已在 3.2 Å 分辨率下确定。该结构域包含一个延伸的 N 末端臂和五个 α 螺旋。抑制子-操纵子复合物的模型构建研究表明，α-螺旋，尤其是这些螺旋的 N 末端部分，可能为蛋白质-DNA 相互作用提供有用的表面。
The structure of the operator-binding domain of the λ repressor has been determined at 3.2 Å resolution. This domain contains an extended N-terminal arm and five α-helices. Model-building studies of the repressor–operator complex suggest that α-helices, especially the N-terminal parts of these helices, may provide a useful surface for protein–DNA interactions.