Clonal spread of IMP-1-producing Pseudomonas aeruginosa in two hospitals in Singapore

Clonal spread of IMP-1-producing Pseudomonas aeruginosa in two hospitals in Singapore
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DOI:
10.1128/jcm.42.11.5378-5380.2004
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发表时间:
2004-11-01
影响因子:
9.4
通讯作者:
Sng, LH
Sng, LH
中科院分区:
医学2区
文献类型:
--
作者:
Koh, TH;Wang, GCY;Sng, LH

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对36株碳青霉烯类耐药铜绿假单胞菌进行了研究。脉冲场凝胶电泳显示存在两个克隆。其中一个克隆携带的bla(IMP-1)基因与日本首次描述的基因相同。另一个克隆携带含有四个沉默突变的bla(IMP-1)变体。一个具有独特脉冲场凝胶电泳模式的分离物含有bla(IMP-7)。
Thirty-six isolates of carbapenem-resistant Pseudomonas aeruginosa were studied. Pulsed-field gel electrophoresis revealed the presence of two clones. One clone carried a bla(IMP-1) gene identical to that first described in Japan. The other clone carried a bla(IMP-1) variant containing four silent mutations. One isolate with a unique pulsed-field gel electrophoresis pattern contained bla(IMP-7).