The long-term behavioral effects of prenatal alcohol exposure in rats.
The long-term behavioral effects of prenatal alcohol exposure in rats.
复制标题
产前酒精暴露对大鼠的长期行为影响。
DOI：
10.1111/j.1530-0277.1990.tb01225.x
复制
发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Riley,EP
中科院分区：
文献类型：
--
作者：
Riley,EP
产前接触酒精会导致以后生活中的各种行为障碍。许多关于酒精对动物行为致畸作用的报告都集中在评估年轻动物上。本文的目的是回顾妊娠期酒精暴露对动物的一些更持久的行为后果。它并不是一个全面的综述，而是侧重于选定的研究。结论是，产前接触酒精确实会产生长期持续的影响，尽管其中一些影响可能只发生在充满挑战或压力的情况下。据推测，随着动物的成熟，补偿机制或策略会发展来补偿这些功能障碍。因此，只有当这些补偿系统因压力、复杂的测试程序或年老而崩溃时，行为问题才可能被发现。
Prenatal exposure to alcohol can cause a variety of behavioral disturbances later in life. Many of the reports in animals of the behavioral teratogenic effects of alcohol have focused on assessing younger animals. The purpose of this paper is to review some of the longer lasting behavioral consequences of gestational alcohol exposure in animals. It is not meant as a comprehensive review, but rather focuses on selected studies. It is concluded that prenatal alcohol exposure does have long lasting effects, although some of these might only occur under challenging or stressful circumstances. It is hypothesized that as the animal matures compensatory mechanisms or strategies develop to compensate for these dysfunctions. Thus, behavioral problems may only be detected when these compensatory systems break down, either as a result of stress, because of complex testing procedures, or old age.