Single joint perturbation during gait: Preserved compensatory response pattern in spinal cord injured subjects
Single joint perturbation during gait: Preserved compensatory response pattern in spinal cord injured subjects
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DOI：
10.1016/j.clinph.2007.03.022
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发表时间：
2007-07-01
影响因子：
4.7
通讯作者：
Dietz, Volker
中科院分区：
文献类型：
--
作者：
Field-Fote, Edelle C.;Dietz, Volker
目的：运动过程中对传入信息的反应是在脊髓水平组织的，但由棘上中枢调节。本研究的目的是探讨是否脊髓上的影响影响的行为复杂的肌电图（EMG）的反应，以单肢扰动在walking.Methods：与电机完全（MCSCI），电机不完全脊髓损伤（MISCI），和非残疾人（ND）的科目参加。髋关节或膝关节的轨迹在摆动阶段的早期或晚期被机器人装置短暂地阻止。结果：脊髓损伤者和ND者的扰动诱发的肌电图反应在基本结构上相似，但SCI者的胫前肌起始时间延迟。在所有组中，后期波动（即，在摆动-站立过渡附近）与较短的肌肉起始时间和较高的EMG振幅相关。膝关节扰动与较短的肌肉反应开始时间，而髋关节扰动引起较高的反应幅度。EMG反应也引起了对侧的肌肉turbation.Conclusions：这些数据表明，神经元回路内的脊髓剥夺正常的脊髓上的输入响应摆动相位扰动的方式是类似的完整的脊髓。成年人的脊髓能够产生复杂的，与在人类婴儿和脊椎动物的研究中观察到的非常相似的相位适当的响应。(c)2007年国际临床神经生理学联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objective: Responses to afferent input during locomotion are organized at the spinal level but modulated by supraspinal centers. The study aim was to examine whether supraspinal influences affect the behavior of complex electromyographic (EMG) responses to single limb perturbations during walking.Methods: Subjects with motor-complete (MCSCI), motor-incomplete spinal cord injury (MISCI), and non-disabled (ND) subjects participated. Hip or knee joint it trajectory was briefly arrested by a robotic device at early or late swing phase. EMG responses from muscles of both legs were analyzed.Results: Perturbation-induced EMG responses of spinal cord injured and ND individuals were similar in basic structure, with the exception that tibialis anterior onset times were delayed for SCI subjects. Across all groups, perturbations in late swing (i.e., near the swing-tostance transition) were associated with shorter muscle onset times and higher EMG amplitudes. Knee perturbations were associated with shorter muscle response onset times, while hip perturbations elicited higher response amplitudes. EMG responses were also evoked in muscles contralateral to the perturbation.Conclusions: These data indicate that neuronal circuits within the spinal cord deprived of normal supraspinal input respond to swing phase perturbations in a manner that is similar to that of the intact spinal cord.Significance: The adult human spinal cord is capable of generating complex, phase-appropriate responses much as has been observed in studies of human infants and in spinal animals. (c) 2007 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.