Sex differences in anxiety and depression clinical perspectives.
Sex differences in anxiety and depression clinical perspectives.
复制标题
焦虑和抑郁症临床观点的性别差异。
DOI：
10.1016/j.yfrne.2014.05.004
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发表时间：
2014-08
影响因子：
7.4
通讯作者：
Neill Epperson C
中科院分区：
文献类型：
--
作者：
Altemus M;Sarvaiya N;Neill Epperson C
情绪和焦虑障碍的性别差异是突出的，并可能提供一个窗口，在男性和女性的情感障碍的发病和维持机制。随着大脑结构、功能和压力反应的性别差异，以及生殖激素、社会期望和经验的差异，我们面临的挑战是了解哪些性别差异与情感疾病有关。这篇综述将集中在情感障碍的性别差异的临床方面，包括跨发育阶段的性别差异的出现和生殖事件的影响。生物，文化和经验的因素，可能是情绪和焦虑症的现象学性别差异的基础进行了讨论。
Sex differences are prominent in mood and anxiety disorders and may provide a window into mechanisms of onset and maintenance of affective disturbances in both men and women. With the plethora of sex differences in brain structure, function, and stress responsivity, as well as differences in exposure to reproductive hormones, social expectations and experiences, the challenge is to understand which sex differences are relevant to affective illness. This review will focus on clinical aspects of sex differences in affective disorders including the emergence of sex differences across developmental stages and the impact of reproductive events. Biological, cultural, and experiential factors that may underlie sex differences in the phenomenology of mood and anxiety disorders are discussed.