The multifaceted presentation of syphilitic chorioretinitis examined by multimodal imaging: A case series.
The multifaceted presentation of syphilitic chorioretinitis examined by multimodal imaging: A case series.
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DOI：
10.1016/j.ajoc.2022.101434
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发表时间：
2022-06
影响因子：
--
通讯作者：
Nicolò M
中科院分区：
文献类型：
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作者：
Ferro Desideri L;Rosa R;Musetti D;Vagge A;Vena A;Bassetti M;Traverso CE;Nicolò M
眼梅毒也被称为“伟大的假面舞者”，因为与这种感染相关的各种临床特征。虽然脉络膜视网膜炎是后极最常见的表现，但也可以描述其他临床实体，包括视网膜血管炎、视盘疾病、坏死性血管炎和急性梅毒性后placoid脉络膜视网膜病变（ASPPC）。
后者是梅毒的一种罕见的眼部表现，其病理生理仍不清楚；然而，多模态成像，包括光学相干断层血管造影（OCTA），使我们能够更好地描述其病理生理和临床过程。
在这项研究中，我们报告了3例不同的梅毒相关脉络膜视网膜病变患者的病例系列；在这方面，多模态成像的作用已经出现了一个非常有用的方法，以便更好地了解梅毒脉络膜视网膜病变的病理生理学。这可以帮助临床医生（包括眼科医生和传染病专家）早期治疗和预防与这种可怕疾病相关的严重眼部并发症。
Ocular syphilis is also known as the ‘great masquerader’ for the wide variety of clinical features associated with this infection. Although chorioretinitis represents the most frequent manifestation in the posterior pole, other clinical entities can be described, including retinal vasculitis, optic disc disorders, necrotizing vasculitis and acute syphilitic posterior placoid chorioretinopathy (ASPPC).
This latter is an infrequent ocular manifestation of syphilis, whose pathophysiology remains still unknown; however, multimodal imaging, including optical coherence tomography angiography (OCTA), has enabled us to better describe its pathophysiology and clinical course.
In this study we report a case series of 3 different patients with syphilis-related chorioretinopathies; in this regard, the role of multimodal imaging has emerged has an extremely useful approach in order to better understand the pathophysiology of syphilitic chorioretinopathies. This could help clinicians (both ophthalmologist and infectious disease specialists) to early treat and prevent the severe ocular complications related to this fearsome disease.