Plasmonic-3D photonic crystals microchip for surface enhanced Raman spectroscopy
Plasmonic-3D photonic crystals microchip for surface enhanced Raman spectroscopy
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DOI：
10.1016/j.bios.2019.111596
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发表时间：
2019-10-15
影响因子：
12.6
通讯作者：
Chen, Xudong
中科院分区：
文献类型：
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作者：
Chen, Guojian;Zhang, Kelian;Chen, Xudong
采用磁控溅射方法在疏水化的二氧化硅光子晶体表面沉积银，制备了三维光子晶体上的银岛等离子体-介电混合衬底。在没有典型的“热点”如纳米间隙的情况下，可以实现显著的拉曼增强，这归因于增强的电磁场和等离子体纳米颗粒的散射以及通过慢光子效应增强的轻物质相互作用。混合基质对腺嘌呤的检测限达到nM水平，计算的增强因子为1.13 x 10（7），比传统的纳米球上贵金属膜（FON）对照组高出三个数量级。此外，基于混合基底的微芯片很容易实现，通过超疏水浓缩实现微检测。三维光子晶体上的银岛由于其简单的制备方法和有效的拉曼增强效应，在化学传感器、拉曼成像和生物检测等领域具有广阔的应用前景。
Plasmonic-dielectic hybrid substrates of Ag-islands on three-dimensional photonic crystals are fabricated through magnetron sputtering of silver onto hydrophobized silica photonic crystals, free from etching process. Without typical "hot-spots" such as nanogaps, significant Raman enhancements can be achieved, attributed to the enhanced electromagnetic field and scattering of the plasmonic nanoparticles as well as the enhanced light matter interaction by the slow photon effects. The detection limit for adenine by the hybrid substrates reaches nM level, with a calculated enhancement factor of 1.13 x 10(7), which is three orders of magnitude higher than the conventional noble metal film over nanosphere (FON) control group. Furthermore, microchips based on the hybrid substrates are facilely achieved, enabling micro-detection through super hydrophobic concentration. The facile fabrication and effective Raman enhancements make the Ag-islands on 3D photonic crystals promising candidates in the field of chemical sensors, Raman mapping and bioassays.