Taste thresholds in twins and siblings.
Taste thresholds in twins and siblings.
复制标题
双胞胎和兄弟姐妹的味觉阈值。
DOI：
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发表时间：
1967
期刊：
影响因子：
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通讯作者：
E. Glanville
中科院分区：
文献类型：
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作者：
A. Kaplan;R. Fischer;A. Karras;F. Griffin;W. Powell;R. Marsters;E. Glanville
Taste thresholds for the majority of compounds follow monomodal or approximately ' Gaussian ' distributions. Quinine is a bitter-tasting representative of these ' Gaussian ' compounds, and a positive correlation has been observed between high taste threshold for quinine and high thresholds for a large number of other substances, including sodium chloride, sucrose, urea, phenylalanine, amphetamine, chlorpromazine, methlylene blue, etc. (Fischer and Griffin, 1964). Pedigree and population studies of taste thresholds, however, have been largely limited to the bitter-tasting phenylthiourea (' PTC ') type antithyroid compounds containing the characteristic H-I^-C = S grouping. Taste thresholds for members of this group, which includes 6-n-propylthiouracil (PROP), i-methyl-2-mercaptoimidazole, etc., follow bimodal distributions in a population. Fox (1931) characterized the individuals belonging to one mode as " tasters " and those belonging to the other mode as " nontasters " of ' PTC ' (after ' phenylthiocarbamide ', a misnomer for phenylthiourea) and related compounds (Fox, 1932). Blakeslee and Salmon (1931) and, independently, Snyder (1931) observed that inability to taste phenylthiourea appeared to be inherited in
