Problems in three Japanese drug users with Human Immunodeficiency Virus infection

Problems in three Japanese drug users with Human Immunodeficiency Virus infection
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DOI:
10.2152/jmi.55.156
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发表时间:
2008-02-01
影响因子:
0.7
通讯作者:
Yamamoto, Yoshihiko
Yamamoto, Yoshihiko
中科院分区:
其他
文献类型:
--
作者:
Kuwahara, Takeshi;Nakakura, Takahiro;Yamamoto, Yoshihiko

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在日本,感染人类免疫缺陷病毒(艾滋病毒)的人数正在增加。他们中的大多数是与男性发生性关系的男性,其中一部分人在性交时服用药物作为“性药物”。特别是亚硝酸戊酯、甲基苯丙胺、5-甲氧基-N,N-二异丙基色胺(5-MeO-DIPT; Foxy)和3,4亚甲二氧基-甲基苯丙胺(MDMA; Ecastine)被使用,并且它们有时引起身体和精神障碍。然而,实际的药物诱导的麻烦,日本HIV感染的吸毒者还没有足够的讨论,在这份报告中,我们描述了三例HIV感染,一例严重的神经阻滞剂恶性综合征(NMS)后,采取5-MeO-DIPT,一个案件与持续惊厥,由于多种药物的摄入量和横纹肌溶解症,由于非主观甲基苯丙胺的摄入量。通过这些案例,我们提出并讨论了与艾滋病毒感染者之间的药物使用相关的几个基本问题。
Numbers of individuals infected with Human Immunodeficiency Virus (HIV) are increasing in Japan. The majority of them are Men who have sex with men and a part of them take drugs as 'Sex drug' at their sexual intercourse. Especially, Amyl nitrite, Methamphetamine, 5-methoxy-N, N-diisopropyltryptamine (5-MeO-DIPT; Foxy), and 3, 4methylenedioxy-methamphetamine (MDMA; Ecstasy) are used, and they sometimes cause the physical and mental disorders. However, the actual drug inducing troubles among Japanese HIV-infected drug users had not yet been discussed enough.In this report, we describe three cases with HIV infection; a case developed severe neuroleptic malignant syndrome (NMS) after taking 5-MeO-DIPT, a case with persistent convulsion due to multiple drug intake and a case with rhabdomyolysis due to the non-subjective methamphetamine intake. Through these cases, we raise and discuss several underlying problems associated with drug use among HIV-infected individuals.