Main characteristics and participation rate of European adolescents included in the HELENA study.
Main characteristics and participation rate of European adolescents included in the HELENA study.
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DOI：
10.1186/0778-7367-70-14
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发表时间：
2012-06-19
期刊：
影响因子：
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通讯作者：
Moreno LA
中科院分区：
文献类型：
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作者：
Béghin L;Huybrechts I;Vicente-Rodríguez G;De Henauw S;Gottrand F;Gonzales-Gross M;Dallongeville J;Sjöström M;Leclercq C;Dietrich S;Castillo M;Plada M;Molnar D;Kersting M;Gilbert CC;Moreno LA
参与率和应答率是横断面大规模流行病学研究的关键问题。本文的目的是描述研究人群，并评估参与HELENA研究的男性和女性青少年的参与和反应率以及关键营养状况变量。采用多阶段随机整群抽样，目标样本为3000名年龄在[12.5 - 17.5]岁之间的青少年，按地理位置和年龄分层。比较了参与者和非参与者（NP）的信息，并讨论了特定问卷的参与率和应答率。3865名[12.5 ~ 17.5]岁的青少年（1,845名女性）参加了HELENA研究，其中1,076名（568名女性）参加了血液采样。共有3528名青少年（女性1845名）进行统计分析。不同国家的学校和班级的参与率差异很大。参与班学生的参与率在不同国家之间也存在显著差异。性别比例，平均年龄和BMI在每个中心内NP和参与的青少年之间，以及在整个样本中是相似的。对于所有纳入数据库的问卷，问卷的回复率都很高（问题完成率超过80%）。从这项研究中可以得出结论，尽管在比较参与者和非参与者之间的关键研究变量时没有发现偏差，但各国之间的参与率差异很大。问卷的回应率非常高。考虑到HELENA研究中观察到的机会和障碍，未来调查青少年生活方式和健康的研究可以优化他们的方法。
Participation rate and response rate are key issues in a cross sectional large-scale epidemiological study. The objective of this paper is to describe the study population and to evaluate participation and response rate as well as the key nutritional status variables in male and female adolescents involved in the HELENA study. A multi-stage random cluster sampling with a target sample of 3000 adolescents aged [12.5 to 17.5] years, stratified for geographical location and age, was carried out. Information for participants and non-participants (NP) was compared, and participation and response rates to specific questionnaires were discussed. 3,865 adolescents aged [12.5 to 17.5] years (1,845 females) participated in the HELENA study, of whom 1,076 (568 females) participated in the blood sampling. 3,528 (1,845 females) adolescents were finally kept for statistical analysis. Participation rates for the schools and classes differed importantly between countries. The participation rate of pupils within the participating classes also differed importantly between countries. Sex ratio, mean age and BMI were similar between NP and participating adolescents within each centre, and in the overall sample. For all the questionnaires included in the database, the response rate of questionnaires was high (more than 80% of questions were completed). From this study it could be concluded that participation rate differed importantly between countries, though no bias could be identified when comparing the key study variables between participants and non-participants. Response rate for questionnaires was very high. Future studies investigating lifestyle and health in adolescents can optimize their methods when considering the opportunities and barriers observed in the HELENA study.