Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems.
Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems.
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DOI：
10.1186/s42238-021-00061-5
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发表时间：
2021-02-18
影响因子：
3.7
通讯作者：
Hindocha C
中科院分区：
文献类型：
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作者：
Moltke J;Hindocha C
公众和医学界对大麻二酚（CBD）的兴趣一直在上升，CBD现在可以从各种来源获得。关于低剂量CBD对压力，焦虑和睡眠问题等结果的影响的研究很少，因此我们对CBD用户进行了在线调查，以更好地了解CBD的使用模式，剂量和自我感知的影响。样本包括387名当前或过去的CBD用户，他们回答了20个问题的在线调查。该调查通过电子邮件数据库和社交媒体发送给CBD用户。参与者报告了基本的人口统计数据，CBD使用模式，使用原因以及对焦虑，睡眠和压力的影响。样本（N = 387）包括61.2%的女性，大多数年龄在25 - 54岁之间（72.2%），主要在英国（77.4%）。使用CBD的前四个原因是自我感知的焦虑（42.6%），睡眠问题（42.5%），压力（37%）和一般健康和福祉（37%）。54%的人报告每天使用少于50毫克CBD，72.6%的人舌下使用CBD。调整后的logistic模型显示，女性使用CBD进行一般健康和幸福[OR 0.45，95%CI 0.30 - 0.72]和锻炼后肌肉酸痛[OR 0.46，95%CI 0.24 - 0.91]的几率低于男性，但使用CBD进行自我感知焦虑[OR 1.60，95%CI 0.30 - 0.72]的几率高于男性。95%CI 0.02 - 2.49]和失眠[OR 1.87，95%CI 1.13 - 3.11]。老年人使用CBD治疗一般健康和福祉，压力，锻炼后肌肉酸痛，焦虑，皮肤状况，注意力集中和睡眠的几率较低，但使用CBD治疗疼痛的几率较高。受访者报告说，CBD的使用对那些使用该药物治疗这些疾病的人的压力，睡眠问题和焦虑有效。这项调查表明，CBD使用者服用这种药物来管理自我感知的焦虑，压力，睡眠和其他症状，通常剂量较低，这些模式因人口统计学特征而异。需要进一步的研究来了解低剂量，代表一般用户，可能会影响心理健康症状，如压力，焦虑和睡眠问题。在线版本包含补充材料，可通过10.1186/s42238 - 021 - 00061 - 5获得。
Public and medical interest in cannabidiol (CBD) has been rising, and CBD is now available from various sources. Research into the effects of low-dose CBD on outcomes like stress, anxiety, and sleep problems have been scarce, so we conducted an online survey of CBD users to better understand patterns of use, dose, and self-perceived effects of CBD. The sample consisted of 387 current or past-CBD users who answered a 20-question online survey. The survey was sent out to CBD users through email databases and social media. Participants reported basic demographics, CBD use patterns, reasons for use, and effects on anxiety, sleep, and stress. The sample (N = 387) consisted of 61.2% females, mostly between 25 and 54 years old (72.2%) and primarily based in the UK (77.4%). The top 4 reasons for using CBD were self-perceived anxiety (42.6%), sleep problems (42.5%), stress (37%), and general health and wellbeing (37%). Fifty-four per cent reported using less than 50 mg CBD daily, and 72.6% used CBD sublingually. Adjusted logistic models show females had lower odds than males of using CBD for general health and wellbeing [OR 0.45, 95% CI 0.30–0.72] and post-workout muscle-soreness [OR 0.46, 95%CI 0.24–0.91] but had higher odds of using CBD for self-perceived anxiety [OR 1.60, 95% CI 0.02–2.49] and insomnia [OR 1.87, 95% CI 1.13–3.11]. Older individuals had lower odds of using CBD for general health and wellbeing, stress, post-workout sore muscles, anxiety, skin conditions, focusing, and sleep but had higher odds of using CBD for pain. Respondents reported that CBD use was effective for stress, sleep problems, and anxiety in those who used the drug for those conditions. This survey indicated that CBD users take the drug to manage self-perceived anxiety, stress, sleep, and other symptoms, often in low doses, and these patterns vary by demographic characteristics. Further research is required to understand how low doses, representative of the general user, might impact mental health symptoms like stress, anxiety, and sleep problems. The online version contains supplementary material available at 10.1186/s42238-021-00061-5.