Donor-recipient height ratio and outcomes in pediatric heart transplantation
Donor-recipient height ratio and outcomes in pediatric heart transplantation
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DOI：
10.1111/petr.12734
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发表时间：
2016-08-01
影响因子：
1.3
通讯作者：
Lytrivi, Irene D.
中科院分区：
文献类型：
--
作者：
Patel, Anjlee;Bock, Matthew J.;Lytrivi, Irene D.
儿童HTx的身高匹配被认为是评估移植物大小的一种上级方法，但没有研究检查身高匹配的供体-受体对的生存优势。我们假设在患有DCM的儿科患者中，过大的供体可以提高生存率，目的是确定该患者组的最佳身高比例。在OPTN数据库中确定了10/89至09/12之间患有DCM的儿童原发性HTx接受者。患者分为三个供者-受者身高和体重比类别。使用Kaplan-Meier分析比较1年和5年生存率，并计算HR。共纳入2133名在研究期间接受HTx的DCM儿童。DRHR的未校正1年生存率更差
Height matching in pediatric HTx has been proposed as a superior method of evaluating graft size, but no studies have examined survival advantage for height-matched donor-recipient pairs. We hypothesized that in pediatric patients with DCM, an oversized donor improves survival and aimed to define the optimal height ratio in this patient group. Pediatric primary HTx recipients with DCM between 10/89 and 09/12 were identified in the OPTN database. Patients were stratified into three donor-recipient height and weight ratio categories. One-and five-yr survival was compared using Kaplan-Meier analysis and HRs were computed. A total of 2133 children with DCM who underwent HTx during the study period were included. Unadjusted one-yr survival was worse for DRHR