Arabidopsis NIP1;1 Transports Antimonite and Determines Antimonite Sensitivity
Arabidopsis NIP1;1 Transports Antimonite and Determines Antimonite Sensitivity
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DOI：
10.1093/pcp/pcp130
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发表时间：
2009-11-01
影响因子：
4.9
通讯作者：
Fujiwara, Toru
中科院分区：
文献类型：
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作者：
Kamiya, Takehiro;Fujiwara, Toru
锑（Sb）对包括植物在内的生物体具有毒性。虽然它不是生物体所必需的，但植物从环境中吸收Sb。在这项研究中，我们确定了锑[Sb（III）]转运拟南芥。我们研究了Sb（III）的耐受性的破坏突变体植物的亚砷酸盐[As（III）]转运蛋白，类胰蛋白酶26内在蛋白（NIPs），因为Sb（III）是类似于As（III）的结构。其中一种突变体nip 1;1表现出对Sb（III）的耐受性，并且积累的Sb较少。此外，表达NIP 1;1的酵母积累的Sb是对照的两倍。这些数据表明，NIP 1;1传输Sb（III），并决定了Sb（III）的敏感性。thaliana.
Antimony (Sb) is toxic to organisms including plants. Although it is not essential to organisms, plants take up Sb from the environment. In this study, we identified an antimonite [Sb(III)] transporter from Arabidopsis thaliana. We examined the Sb(III) tolerance of the disruption mutant plants of arsenite [As(III)] transporters, nodulin 26-like intrinsic proteins (NIPs), since Sb(III) is similar to As(III) in structure. One of the mutants, nip1;1, showed Sb(III) tolerance and accumulated less Sb. Furthermore, yeast expressing NIP1;1 accumulated twice as much Sb as control. These data indicate that NIP1;1 transports Sb(III) and determines the Sb(III) sensitivity of A. thaliana.