In vivo validation of resting full-cycle ratio and diastolic pressure ratio: simultaneous measurement with instantaneous wave-free ratio
In vivo validation of resting full-cycle ratio and diastolic pressure ratio: simultaneous measurement with instantaneous wave-free ratio
复制标题
DOI：
10.1007/s12928-020-00648-4
复制
发表时间：
2020-02-11
影响因子：
3.2
通讯作者：
Matsuo, Hitoshi
中科院分区：
文献类型：
--
作者：
Kawase, Yoshiaki;Omori, Hiroyuki;Matsuo, Hitoshi
在汇总数据的回顾性分析中，认为舒张压比（dPR）和静息全周期比（RFR）与瞬时无波比（iFR）几乎相同。本研究的目的是调查iFR和这些新的静息指标在真实的世界实践中的直接比较。将两个压力导丝插入并放置在同一冠状动脉的远端部分。同时测定iFR和其他静息指标。共对23例患者的54个病变进行了生理学研究。在49个病灶中，还在充血条件下测量iFR和其他静息指数。在静息和充血状态下，iFR与其他静息指标之间的一般相关性均极佳（分别为r（2）= 0.99;平均差异- 0.001 +/- 0.021; p < 0.001; r（2）= 0.99;平均差异- 0.012 +/- 0.025; p < 0.001）。这种相关性在各种亚组分析中得到维持。在3例（3%）病例中，当采用固定的截止点（
The diastolic pressure ratio (dPR) and resting full-cycle ratio (RFR) are considered to be almost identical to the instantaneous wave-free ratio (iFR) in the retrospective analysis of pooled data. The aim of this study was to investigate the direct comparison of iFR and these new resting indexes in real world practice. Two pressure wires were inserted and placed in the distal part of the same coronary artery. The measurement of the iFR and the other resting indexes was performed simultaneously. A total of 54 lesions from 23 patients were subject to physiological study. In 49 lesions, iFR and other resting indexes were also measured in hyperemic conditions. The general correlation between iFR and other resting indexes was excellent in both resting and hyperemic conditions (r(2) = 0.99; mean difference - 0.001 +/- 0.021; p < 0.001; and r(2) = 0.99; mean difference - 0.012 +/- 0.025; p < 0.001, respectively). This correlation was maintained in various subgroup analyses. A diagnostic change between iFR and other resting indexes occurred in three cases (3%) when a fixed cut-off point (