Enantioselective Diels–Alder reactions using a G-triplex DNA-based catalyst
Enantioselective Diels–Alder reactions using a G-triplex DNA-based catalyst
复制标题
DOI：
10.1016/j.catcom.2015.09.012
复制
发表时间：
2016-01
影响因子：
3.7
通讯作者：
Xiaowei Xu;Wuxiang Mao;Feng Lin;Jianlin Hu;Zhiyong He;X. Weng;Chun‐Jiang Wang;Xiang Zhou
中科院分区：
文献类型：
--
作者：
Xiaowei Xu;Wuxiang Mao;Feng Lin;Jianlin Hu;Zhiyong He;X. Weng;Chun‐Jiang Wang;Xiang Zhou
在这项研究中，首次发现G-三链DNA与铜离子配位时，可以在Diels-Alder反应中用作对映选择性催化剂，而无需进一步添加配体。研究了催化剂的效率和选择性。使用紫外 (UV) 光进行动力学测量。通过圆二色性（CD）和核磁共振（NMR）光谱证实了催化剂在水性缓冲液中的稳定性。
In this study, it was found that the G-triplex DNA could be used as an enantioselective catalyst without further addition of ligands in Diels–Alder reactions when coordinated with copper ions, for the first time. The efficiency and selectivity of the catalyst were investigated. The kinetic measurements were made using ultraviolet (UV) light. The stability of the catalyst in aqueous buffer was confirmed by circular dichroism (CD) and nuclear magnetic resonance (NMR) spectra.