Green Tea Consumption and the Risk of Incident Dementia in Elderly Japanese: The Ohsaki Cohort 2006 Study
Green Tea Consumption and the Risk of Incident Dementia in Elderly Japanese: The Ohsaki Cohort 2006 Study
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DOI：
10.1016/j.jagp.2016.07.009
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发表时间：
2016-10-01
影响因子：
7.2
通讯作者：
Tsuji, Ichiro
中科院分区：
文献类型：
--
作者：
Tomata, Yasutake;Sugiyama, Kemmyo;Tsuji, Ichiro
目的：生物学研究表明，绿茶中的某些成分可能对神经认知有保护作用。然而，由于缺乏人类流行病学研究，绿茶消费对痴呆症发病率的影响从未得到证实。这项队列研究的目的是澄清绿茶消费和痴呆症事件之间的联系。方法：在这项为期5.7年的前瞻性队列研究中，通过问卷调查，收集了65岁或以上日本老年人的日常绿茶消费和其他生活方式因素的信息。从公共长期护理保险数据库中检索关于偶发痴呆症的数据。结果：在13,645名参与者中，5.7年痴呆症发病率为8.7%。更频繁地饮用绿茶与较低的痴呆症风险相关(风险比=5杯/天与
Objective: Biologic studies have shown that certain components of green tea may have protective effects on neurocognition. However, because of the lack of human epidemiologic studies, the impact of green tea consumption on the incidence of dementia has never been confirmed. The objective of this cohort study was to clarify the association between green tea consumption and incident dementia. Methods: In this 5.7-year prospective cohort study, using a questionnaire, information on daily green tea consumption and other lifestyle factors was collected from elderly Japanese individuals aged 65 years or more. Data on incident dementia were retrieved from the public Long-term Care Insurance Database. Results: Among 13,645 participants, the 5.7-year rate of incident dementia was 8.7%. More frequent green tea consumption was associated with a lower risk of incident dementia (hazard ratio for >= 5 cups/day versus