Immunogenicity and safety of influenza vaccination in children with inflammatory bowel disease

Immunogenicity and safety of influenza vaccination in children with inflammatory bowel disease
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DOI:
10.1002/ibd.21706
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发表时间:
2012-01-01
影响因子:
4.9
通讯作者:
Wrobel, Iwona
Wrobel, Iwona
中科院分区:
医学2区
文献类型:
--
作者:
deBruyn, Jennifer C. C.;Hilsden, Robert;Wrobel, Iwona

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背景资料:预防疫苗可预防的疾病在炎症性肠病(IBD)中很重要,因为免疫抑制治疗会增加感染的易感性和严重性。然而,免疫抑制疗法可能影响疫苗应答。本研究旨在评价IBD儿童接种流感疫苗的免疫原性和安全性。
Background: Protection against vaccine-preventable diseases is important in inflammatory bowel disease (IBD) because of increased susceptibility and severity of infection with immunosuppressive therapy. However, immunosuppressive therapy may affect vaccine response. This study aimed to evaluate immunogenicity and safety of influenza vaccination in children with IBD.