Polygenic sex determination in vertebrates - is there any such thing?
Polygenic sex determination in vertebrates - is there any such thing?
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DOI：
10.1016/j.tig.2022.12.002
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发表时间：
2023-01
期刊：
影响因子：
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通讯作者：
M. Schartl;A. Georges;J. A. Marshall Graves
中科院分区：
文献类型：
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作者：
M. Schartl;A. Georges;J. A. Marshall Graves
大多数脊椎动物的遗传性别决定(SD)是由单一的主性基因控制的，这确保了1：1的性别比例。然而，更复杂的系统比比皆是，其中有几个被归因于多基因SD(PSD)，在这个系统中，不同基因的多个基因相互作用产生有性表型。在这里，我们检查了脊椎动物中PSD的声明，发现大多数在性染色体周转过程中都是瞬时状态，或者是物种杂交中的异常系统。为了避免对术语的混淆，我们建议对遗传SD系统进行一致的命名。
Genetic sex determination (SD) in most vertebrates is controlled by a single master sex gene, which ensures a 1:1 sex ratio. However, more complex systems abound, and several have been ascribed to polygenic SD (PSD), in which many genes at different loci interact to produce the sexual phenotype. Here we examine claims for PSD in vertebrates, finding that most constitute transient states during sex chromosome turnover, or aberrant systems in species hybrids. To avoid confusion about terminology, we propose a consistent nomenclature for genetic SD systems.