Electrostatic edge instability of lipid membranes
Electrostatic edge instability of lipid membranes
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DOI：
10.1103/physrevlett.82.1598
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发表时间：
1999-02-15
影响因子：
8.6
通讯作者：
Brenner, MP
中科院分区：
文献类型：
--
作者：
Betterton, MD;Brenner, MP
本文研究了静电对带电膜稳定性的影响。我们表明，在低离子强度和高表面电荷密度下，膜上电荷之间的排斥使其不稳定，无法形成空穴。自由直边对于波长大于德拜屏蔽长度的调制是不稳定的。因此，在低离子强度下，膜将分解成囊泡。我们使用这些结果来解释红细胞幽灵中的稳定孔。[S0031-9007(98)08370-7]。
This paper considers the effect of electrostatics on the stability of a charged membrane. We show that at low ionic strength and high surface charge density, repulsion between charges on the membrane renders it unstable to the formation of holes. A free straight edge is unstable to modulations with wavelength longer than the Debye screening length. Hence, at low ionic strength membranes will disintegrate into vesicles. We use these results to interpret stable holes in red blood cell ghosts.[S0031-9007(98)08370-7].