Heart rate ranges in premature neonates using high resolution physiologic data
Heart rate ranges in premature neonates using high resolution physiologic data
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DOI：
10.1038/s41372-018-0156-1
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发表时间：
2018-09-01
影响因子：
2.9
通讯作者：
Spaeder, Michael C.
中科院分区：
文献类型：
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作者：
Alonzo, Corrie J.;Nagraj, Vijay P.;Spaeder, Michael C.
目的已发表的早产儿心率范围的循证证据有限。我们根据孕期和月经后年龄确定早产儿的心率范围。研究设计：对2009年1月至2015年10月间住进弗吉尼亚大学新生儿重症监护病房的早产儿进行回顾性观察研究。研究对象包括23.0/7周至34.6/7周的胎龄。我们按孕期和月经后年龄组对数据进行分层。结果1703名新生儿的超过20亿心率值纳入我们的研究。我们根据孕期和月经后年龄建立了基于百分位数的参考范围。我们的结果显示，出生后最初几周略有增加，随后随着年龄的增长逐渐下降。胎龄越高，基线心率越低。结论了解早产儿的心率参考范围有助于新生儿的床边评估。
Objective There are limited evidence-based published heart rate ranges for premature neonates. We determined heart rate ranges in premature neonates based on gestational and post-menstrual age.Study Design Retrospective observational study of premature neonates admitted to the neonatal intensive care unit at the University of Virginia between January 2009 and October 2015. We included gestational ages between 23 0/7 weeks and 34 6/7 weeks. We stratified data by gestational and post-menstrual age groups.Results Over two billion heart rate values in 1703 neonates were included in our study. We established percentile-based reference ranges based on gestational and post-menstrual age. Our results demonstrate a slight increase in the initial weeks after birth, followed by a gradual decline with age. The baseline heart rate is lower with advancing gestational age.Conclusions Knowing heart rate reference ranges in the premature neonatal population can be helpful in the bedside assessment of the neonate.