Genesis of the dorsal lateral geniculate nucleus in the rhesus monkey: Site and time of origin, kinetics of proliferation, routes of migration and pattern of distribution of neurons
Genesis of the dorsal lateral geniculate nucleus in the rhesus monkey: Site and time of origin, kinetics of proliferation, routes of migration and pattern of distribution of neurons
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DOI：
10.1002/cne.901760103
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发表时间：
1977-11
影响因子：
2.5
通讯作者：
P. Rakić
中科院分区：
文献类型：
--
作者：
P. Rakić
2 至 3 个月大的恒河猴的背外侧膝状体 (LGd) 的放射自显影图显示，仅在 E36、E38、E40 和 E43 注射的动物中，每只恒河猴都在特定胚胎 (E) 或出生后早期 (P) 日暴露于 H3-胸苷 (H3-TdR) 脉冲。在妊娠最后四个月或出生后暴露于 H3-TdR 的动物中，LGd 仅偶尔含有标记的神经胶质细胞。因此，在猴子中，所有前往 LGd 的神经元都是在 165 天妊娠期第一季度末的 8 至 9 天内产生的。
Autoradiograms of the dorsal lateral geniculate body (LGd) in 2‐ to 3‐ month‐old rhesus monkeys, each of which had been exposed to a pulse of H3‐thymidine (H3‐TdR) on a specified embryonic (E) or early postnatal (P) day displayed heavily labeled neurons only in animals injected at E36, E38, E40 and E43. In animals exposed to H3‐TdR during the last four months of gestation or after birth, the LGd contained only an occasional labeled glial cell. In the monkey, therefore, all neurons destined for the LGd are generated during 8 to 9 days at the end of the first quarter of the 165‐day gestational period.