Proteome degradation in ancient bone: Diagenesis and phylogenetic potential
Proteome degradation in ancient bone: Diagenesis and phylogenetic potential
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DOI：
10.1016/j.palaeo.2014.06.026
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发表时间：
2014-12-15
影响因子：
3
通讯作者：
Wadsworth, C.
中科院分区：
文献类型：
--
作者：
Buckley, M.;Wadsworth, C.
在考古和古生物遗址上发现的脊椎动物遗骸的物种组成已被证明是重建过去畜牧业实践以及恢复古生物学和古生态学信息的宝贵信息来源。分子分析提供了一种客观的替代方法，物种鉴定的传统形态学的方法，特别是有用的零碎材料;最有名的是DNA的分析。然而，最近的蛋白质组学技术被证明提供了强大的新方法，从更深的考古记录中获得分子物种鉴定和分子同源性。胶原蛋白是最丰富和最稳定的蛋白质，可以在生物矿化组织中存活数百万年，但几十年来已经确定，许多其他可能更具信息性的非胶原蛋白（NCPs）也长期存在于考古甚至地质记录中。这项研究调查了古骨骼中生物分子存活的潜在机制，以及在多大程度上存活了数十万年的NCP产生了有用的系统发育信息。这些NCP中的一些被证明产生物种特异性的信息，使它们成为理想的古环境推断。(C)2014由Elsevier B.V.出版
The species composition of vertebrate remains found on archaeological and palaeontological sites has proved to be a valuable source of information for reconstructions of past animal husbandry practices as well as for recovering palaeobiological and palaeoecological information. Molecular analyses provide an objective alternative method of species identification to traditional morphological approaches, particularly useful with fragmentary material; the most well-known being the analysis of DNA. However, more recent proteomics techniques are proving to offer powerful new approaches for obtaining molecular species identification and molecular phylogenies from much deeper within the archaeological record. Collagen is the most abundant and stable protein that can survive for millions of years in biomineralised tissues, but it has been well established for several decades that many other, potentially more informative, non-collagenous proteins (NCPs) also survive long into the archaeological and even geological records. This study investigates the potential mechanisms for biomolecule survival in ancient bone, as well as the extent to which the NCPs that do survive over hundreds of thousands of years yield useful phylogenetic information. Some of these NCPs are shown to yield species-specific information making them ideal for palaeoenvironmental inferences. (C) 2014 Published by Elsevier B.V.