Nutritional aspects of HIV-associated wasting in sub-Saharan Africa
Nutritional aspects of HIV-associated wasting in sub-Saharan Africa
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DOI：
10.3945/ajcn.2010.28608d
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发表时间：
2010-04-01
影响因子：
7.1
通讯作者：
Heimburger, Douglas C.
中科院分区：
文献类型：
--
作者：
Koethe, John R.;Heimburger, Douglas C.
艾滋病毒感染和粮食短缺这两种全球流行病对撒哈拉以南非洲的影响尤为严重，需要抗逆转录病毒疗法的患者中有很大一部分营养不良，原因是与艾滋病毒有关的消瘦和营养摄入不足。蛋白质-热量营养不良是该区域成人营养不良的最常见形式，与发病率高有关，并加剧了艾滋病毒的免疫抑制作用。低体重指数（BMI）是晚期营养不良的标志，是早期死亡率的独立预测因子（
The twin global epidemics of HIV infection and food scarcity disproportionately affect sub-Saharan Africa, and a significant proportion of patients who require antiretroviral therapy (ART) are malnourished because of a combination of HIV-associated wasting and inadequate nutrient intake. Protein-calorie malnutrition, the most common form of adult malnutrition in the region, is associated with significant morbidity and compounds the immunosuppressive effects of HIV. A low body mass index (BMI), a sign of advanced malnutrition, is an independent predictor of early mortality (