Developing a conceptual framework for an evaluation system for the NIAID HIV/AIDS clinical trials networks.
Developing a conceptual framework for an evaluation system for the NIAID HIV/AIDS clinical trials networks.
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DOI：
10.1186/1478-4505-7-12
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发表时间：
2009-05-21
影响因子：
4
通讯作者：
Trochim WM
中科院分区：
文献类型：
--
作者：
Kagan JM;Kane M;Quinlan KM;Rosas S;Trochim WM
在全球范围内，呼吁卫生研究组织重新审查其政策和做法，以更有效地满足当前的科学和社会需求，以及公众对问责制日益增长的要求。通过案例研究的方法，作者研究了国家过敏和传染病研究所（美国政府卫生与公众服务部国家卫生研究院的一部分）为最近重组的艾滋病毒/艾滋病临床试验计划开发评估系统所做的努力。在设计，实施和管理全球临床试验项目的挑战被认为是在大规模的科学研究计划的背景下。通过广泛的利益相关者的输入过程中，成功因素的框架，使两个前瞻性的观点，必须在本研究的评价和当前状态评估的重组的目标是在何种程度上理解的DAIDS临床研究网络的利益相关者解决的因素。
Globally, health research organizations are called upon to re-examine their policies and practices to more efficiently and effectively address current scientific and social needs, as well as increasing public demands for accountability. Through a case study approach, the authors examine an effort undertaken by the National Institute of Allergy & Infectious Diseases (part of the National Institutes of Health, Department of Health & Human Services, United States Government) to develop an evaluation system for its recently restructured HIV/AIDS clinical trials program. The challenges in designing, operationalizing, and managing global clinical trials programs are considered in the context of large scale scientific research initiatives. Through a process of extensive stakeholder input, a framework of success factors was developed that enables both a prospective view of the elements that must be addressed in an evaluation of this research and a current state assessment of the extent to which the goals of the restructuring are understood by stakeholders across the DAIDS clinical research networks.