Changes in medication initiation and selection patterns for gestational diabetes management.
Changes in medication initiation and selection patterns for gestational diabetes management.
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妊娠糖尿病管理的药物起始和选择模式的变化。
DOI：
10.1111/1471-0528.17664
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发表时间：
2024
期刊：
影响因子：
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通讯作者：
Osmundson,SarahS
中科院分区：
文献类型：
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作者：
Pham,Amelie;Shi,Rena;Wiese,AndrewD;Spieker,AndrewJ;Phillips,SharonE;Adgent,MargaretA;Grijalva,CarlosG;Osmundson,SarahS
关于妊娠期糖尿病药物使用的最新趋势在以前的文献中没有得到很好的描述。我们确定了参加田纳西州医疗补助计划的孕妇，他们被诊断为GDM，于2007年至2019年分娩。我们按分娩年份(总体和药物类型)研究了GDM的初始用药情况。在研究期间，超过20%的患者至少开了一张GDM药物处方，随着时间的推移，处方数量有显著增加的趋势。从2016年开始，二甲双胍取代格列本脲成为最常见的处方药，这在时间上与不同口服降糖药的安全性和有效性的证据的出现以及ACOG实践建议的相关变化相对应。这些发现突显了实践模式如何有可能随着不断变化的数据而迅速转变。
Recent trends regarding GDM medication use have not been well described in prior literature. We identified pregnant patients enrolled in Tennessee Medicaid with a GDM diagnosis who a delivered in 2007 to 2019. We studied initial GDM medication use by delivery year (overall and by medication type). Over twenty percent of patients filled at least one prescription for GDM medication in the study period, with a significantly increasing prescribing trend over time. Starting in 2016, metformin replaced glyburide as the most common medication prescribed, which corresponds temporally with the emergence of evidence on the safety and effectiveness of different oral hypoglycemic medications and related changes in ACOG practice recommendations. These findings highlight how practice patterns have potential to shift quickly in response to evolving data.