A Hybrid Inverse Problem in the Fluorescence Ultrasound Modulated Optical Tomography in the Diffusive Regime

A Hybrid Inverse Problem in the Fluorescence Ultrasound Modulated Optical Tomography in the Diffusive Regime
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DOI:
10.1137/18m117889x
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发表时间:
2018-04
期刊:
SIAM J. Appl. Math.
影响因子:
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通讯作者:
Wei Li;Yang Yang-Yang;Yimin Zhong
Wei Li;Yang Yang-Yang;Yimin Zhong
中科院分区:
其他
文献类型:
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作者:
Wei Li;Yang Yang-Yang;Yimin Zhong

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研究了扩散区荧光超声调制光学层析成像(FUMOT)中的混合逆问题。证明了在已知某些背景媒质参数的情况下,通过对光子流边界的测量,可以唯一而稳定地重建荧光团在激发频率处的吸收系数和量子效率系数。提出了重建算法,并进行了数值实现。
We investigate a hybrid inverse problem in fluorescence ultrasound modulated optical tomography (fUMOT) in the diffusive regime. We prove that the absorption coefficient of the fluorophores at the excitation frequency and the quantum efficiency coefficient can be uniquely and stably reconstructed from boundary measurement of the photon currents, provided that some background medium parameters are known. Reconstruction algorithms are proposed and numerically implemented as well.