Changes in Standard Metabolism during Long-Term Fasting in Northern Elephant Seal Pups (Mirounga angustirostris)
Changes in Standard Metabolism during Long-Term Fasting in Northern Elephant Seal Pups (Mirounga angustirostris)
复制标题
北象海豹幼崽（Mirounga angustirostris）长期禁食期间标准代谢的变化
DOI：
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发表时间：
1992
期刊：
影响因子：
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通讯作者：
D. Costa
中科院分区：
文献类型：
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作者：
L. Rea;D. Costa
测量体重，身体成分，和O-2 O-消耗率V ~ 2被用来量化的一些因素，影响代谢过程中的第一个4个月的发展在北方象海豹幼崽。在4周的哺乳期内，幼仔的平均体重从42.0 ± 3.5 kg增加到127.3 ± 15.9 kg。到断奶后10周结束时，快速平均体重下降至83.1 ± 1.5 kg。体脂肪从出生时的4%增加到断奶时的48%，但在整个禁食期间保持相对稳定。体重和身体成分的急剧变化，如这些，预计会影响代谢显着。为了验证这一理论，通过开路呼吸测定法测量了从出生到18周龄的幼仔的O-23消耗量。代谢变化与瘦体重增加的相关性最强（r² = .51，P < 0.01）。总的来说，瘦体重和年龄的变化占V to 2变异性的75%（P < 0.01）。此外，在断奶后禁食10周后，两只实验室动物开始进食时，瘦体重特异性V to 2增加了19%。这意味着代谢的抑制，可能是长期禁食期间能量守恒的适应。
Measurements of body mass, body composition, and O₂ consumption rate V̇o2 were used to quantify some of the factors that influence metabolism during the first 4 mo of development in the northern elephant seal pup. During the 4-wk nursing period, average body mass of the pups increased from 42.0 ± 3.5 kg to 127.3 ± 15.9 kg. By the end of the 10-wk postweaning fast mean body mass declined to 83.1 ± 1.5 kg. Body fat increased from 4% of body mass near birth to approximately 48% at weaning but remained relatively constant throughout the fast. Dramatic changes in body mass and body composition such as these would be expected to influence metabolism significantly. To test this theory, O₂ consumption was measured in pups from birth to 18 wk of age through open-circuit respirometry. Changes in metabolism were correlated most strongly with increases in lean body mass (r² = .51, P < 0.01). Together, changes in lean body mass and age accounted for 75% of the variability seen in V̇o2 (P < 0.01). In addition, a 19% increase in lean mass-specific V̇o2 was documented with the onset of feeding in two laboratory animals, after a 10-wk postweaning fast. This implies a depression of metabolism, possibly as an adaptation for energy conservation during long-term fasting.
人类维持体重的能量需求：身体尺寸和成分的影响。
影响因子：
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作者：
Forbes,GB;Brown,MR
通讯作者：
Brown,MR
鼻逆流热交换对北象海豹 Mirounga angustirostris 水平衡的贡献。
DOI：
10.1242/jeb.113.1.447
发表时间：
1984
期刊：
The Journal of experimental biology
影响因子：
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作者：
Huntley,AC;Costa,DP;Rubin,RD
通讯作者：
Rubin,RD