Sex and Pain Perception and Analgesia
Sex and Pain Perception and Analgesia
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DOI：
10.1016/s0034-7094(11)70091-5
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发表时间：
2011-11-01
影响因子：
1
通讯作者：
Posso, Irimar de Paula
中科院分区：
文献类型：
--
作者：
de Araujo Palmeira, Claudia Carneiro;Ashmawi, Hazem Adel;Posso, Irimar de Paula
帕尔梅拉CCA，Ashmawi HA，Posso IP -性与疼痛感知和镇痛。大量的证据表明，男性和女性的经验是不同的，以及对某些类别的止痛药的答案。实验室实验表明，女性的疼痛阈值比男性低，这与热、冷、压力和电刺激等有害刺激引起的疼痛有关。疼痛是一种在兴奋性和抑制性控制的各种机制的影响下的动态现象。与性别相关的疼痛感知差异可能与女性的痛觉过敏有关，但也与女性疼痛抑制系统的活动减退有关。除了显示一些性腺激素，中枢神经系统和疼痛的关系，这篇综述的目的是提供参考点的疼痛的病理生理学的最有趣的方面之一的讨论：疼痛刺激的存在与性别有关的差异。
Palmeira CCA, Ashmawi HA, Posso IP - Sex and Pain Perception and Analgesia.Sex is an important factor in painful experience modulation. Large volume of evidence shows that experience is different for males and females, as well as the answer to some classes of analgesics. Laboratory experiments suggest that women have a lower pain threshold than men related to pain from noxious stimuli such as heat, cold, pressure and electrical stimulation. Pain is a dynamic phenomenon under the influence of various mechanisms of excitatory and inhibitory control. The differences in pain perception related to sex may be associated with hyperalgesia in women, but also to the hypoactivity of the inhibitory system of pain in females. The purpose of this review besides showing some relationship for gonadal hormones, central nervous system and pain is to provide reference points for the discussion of one of the most intriguing aspects of the pathophysiology of pain: the differences in the presence of painful stimuli related to gender.