SODEFRIN - A FEMALE-ATTRACTING PEPTIDE PHEROMONE IN NEWT CLOACAL GLANDS

SODEFRIN - A FEMALE-ATTRACTING PEPTIDE PHEROMONE IN NEWT CLOACAL GLANDS
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DOI:
10.1126/science.7886452
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发表时间:
1995-03-17
期刊:
影响因子:
56.9
通讯作者:
HAYASHI, H
HAYASHI, H
中科院分区:
综合性期刊1区
文献类型:
--
作者:
KIKUYAMA, S;TOYODA, F;HAYASHI, H

文献摘要

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从雄性红腹蝾螈(Cynops pyrrhogaster)泄殖腔的腹腺中分离出一种名为sodefrin的十肽。天然肽和合成肽一样,具有吸引女性的活性。Sodefrin被发现在腹腺上皮细胞的顶端部分。Sodefrin是明显的物种特异性,因为它不吸引雌性的Cynops ensicauda。这是第一个两栖类信息素被确定和第一个肽信息素确定在脊椎动物。
A decapeptide called sodefrin was isolated from the abdominal gland of the cloaca of the male red-bellied newt, Cynops pyrrhogaster. The native peptide, as well as the synthetic one, had a female-attracting activity. Sodefrin was found in the apical portion of the epithelial cells of the abdominal gland. Sodefrin is apparently species specific because it did not attract females of Cynops ensicauda. This is the first amphibian pheromone to be identified and the first peptide pheromone identified in a vertebrate.